[HTML][HTML] Gastric cancer treatment: recent progress and future perspectives

WL Guan, Y He, RH Xu - Journal of hematology & oncology, 2023 - Springer
Gastric cancer (GC) is one of the most common malignancies worldwide. Most patients are
diagnosed at advanced stages due to the subtle symptoms of earlier disease and the low …

[HTML][HTML] Targeting LAG-3, TIM-3, and TIGIT for cancer immunotherapy

L Cai, Y Li, J Tan, L Xu, Y Li - Journal of hematology & oncology, 2023 - Springer
In one decade, immunotherapy based on immune checkpoint blockades (ICBs) has become
a new pillar of cancer treatment following surgery, radiation, chemotherapy, and targeted …

[HTML][HTML] Nanomaterials in tumor immunotherapy: new strategies and challenges

X Zhu, S Li - Molecular Cancer, 2023 - Springer
Tumor immunotherapy exerts its anti-tumor effects by stimulating and enhancing immune
responses of the body. It has become another important modality of anti-tumor therapy with …

[HTML][HTML] Recent advances in targeted strategies for triple-negative breast cancer

S Zhu, Y Wu, B Song, M Yi, Y Yan, Q Mei… - Journal of Hematology & …, 2023 - Springer
Triple-negative breast cancer (TNBC), a highly aggressive subtype of breast cancer,
negatively expresses estrogen receptor, progesterone receptor, and the human epidermal …

[HTML][HTML] Gamma delta T-cell-based immune checkpoint therapy: attractive candidate for antitumor treatment

Z Gao, Y Bai, A Lin, A Jiang, C Zhou, Q Cheng, Z Liu… - Molecular Cancer, 2023 - Springer
As a nontraditional T-cell subgroup, γδT cells have gained popularity in the field of
immunotherapy in recent years. They have extraordinary antitumor potential and prospects …

[HTML][HTML] Bispecific antibody targeting TGF-β and PD-L1 for synergistic cancer immunotherapy

T Li, X Wang, M Niu, M Wang, J Zhou, K Wu… - Frontiers in …, 2023 - frontiersin.org
The PD-1/PD-L1 signaling pathway plays a crucial role in cancer immune evasion, and the
use of anti-PD-1/PD-L1 antibodies represents a significant milestone in cancer …

[HTML][HTML] Immune checkpoint inhibitor combinations—current and emerging strategies

RJ Walsh, R Sundar, JSJ Lim - British Journal of Cancer, 2023 - nature.com
In an attempt to overcome resistance to immune checkpoint inhibitors (ICI), an ever-
increasing number of trials are exploring combination treatment approaches. Outcomes of a …

[HTML][HTML] Combining single-cell sequencing and spatial transcriptome sequencing to identify exosome-related features of glioblastoma and constructing a prognostic …

S Zhao, Q Wang, K Ni, P Zhang, Y Liu, J Xie… - Frontiers in …, 2023 - frontiersin.org
Background Glioblastoma (GBM) is a malignant primary brain tumor. This study focused on
exploring the exosome-related features of glioblastoma to better understand its cellular …

[HTML][HTML] Biological and clinical aspects of metastatic spinal tumors

J Litak, W Czyżewski, M Szymoniuk, L Sakwa… - Cancers, 2022 - mdpi.com
Simple Summary Spine metastases are a common life-threatening complication of
advanced-stage malignancies and often result in poor prognosis. Symptomatic spine …

Novel immune checkpoint targets: A promising therapy for cancer treatments

M Patwekar, N Sehar, F Patwekar, A Medikeri… - International …, 2024 - Elsevier
The immune system frequently comprises immunological checkpoints. They serve as a
barrier to keep the immune system from overreacting and damaging cells that are robust …