The development of allergic disease involves the production of IgE antibodies upon allergen
exposure in a process called sensitization. IgE binds to receptors on the surface of mast …

Food allergy imposes a severe global health burden, and thus, there is a dire need for safe
and effective treatments. Allergen-specific immunotherapy (AIT) is currently the only …

Mud crab (Scylla serrata), which is widely consumed, can cause severe allergic symptoms.
Eight linear epitopes and seven conformational epitopes of tropomyosin (TM) from S. serrata …

The introduction of plant extracts to mitigate the symptoms of “hay fever”, about a century
ago, led to discoveries beginning sixty years ago on determining the sequences and …

Summary Background Cross‐linking of IgE antibody by specific epitopes on the surface of
mast cells is a prerequisite for triggering symptoms of peanut allergy. IgE epitopes are …

The phenomenon of cross-reactivity between allergenic proteins plays an important role to
understand how the immune system recognizes different antigen proteins. Allergen proteins …

Background IgE antibodies specific for the major birch pollen allergen frequently cross‐react
with B et v 1 homologous food proteins, for example C or a 1 in hazelnut and Mal d 1 in …

The one-bead-one-compound (OBOC) combinatorial peptide library is a powerful tool to
identify ligand and receptor interactions. Here, we applied the OBOC library technology to …

Pru p 3, one of the most representative proteins of the lipid transfer proteins (LTPs), is
responsible for clinical allergic reactions to food of peach origin. The identification of Pru p 3 …

Phage peptide display technology has been used to identify IgE‐binding mimotopes (mimics
of natural epitopes) that mimic conformational epitopes. This approach is effective in the …