Aging is associated with changes in circulating levels of various molecules, some of which
remain undefined. We find that concentrations of circulating taurine decline with aging in …

The data output from microbiome research is growing at an accelerating rate, yet mining the
data quickly and efficiently remains difficult. There is still a lack of an effective data structure …

Motivation Seurat is one of the most popular software suites for the analysis of single-cell
RNA sequencing data. Considering the popularity of the tidyverse ecosystem, which offers a …

Cellular omics such as single-cell genomics, proteomics, and microbiomics allow the
characterization of tissue and microbial community composition, which can be compared …

The growth of omic data presents evolving challenges in data manipulation, analysis and
integration. Addressing these challenges, Bioconductor provides an extensive community …

The binding of platelet-derived growth factor D (PDGF-DD) to the NKp44 receptor activates a
distinct transcriptional program in primary IL-2 expanded human natural killer (NK) cells. We …

Ebola virus disease is a severe hemorrhagic fever with a high fatality rate. We investigate
transcriptome profiles at 3 h, 1 day, and 7 days after vaccination with Ad26. ZEBOV and MVA …

Activation of natural killer (NK) cell function is regulated by cytokines, such as IL-2, and
secreted factors upregulated in the tumor microenvironment, such as platelet-derived growth …

In addition to the stage of transcriptional initiation, the production of mRNAs is regulated
during elongation. Accordingly, the synthesis of mRNAs by RNA polymerase II (RNAPII) in …

The data output from microbiome research is growing at an accelerating rate, yet mining the
data quickly and efficiently remains difficult. There is still a lack of effective data structure to …