Taurine deficiency as a driver of aging
Aging is associated with changes in circulating levels of various molecules, some of which
remain undefined. We find that concentrations of circulating taurine decline with aging in …
remain undefined. We find that concentrations of circulating taurine decline with aging in …
[HTML][HTML] MicrobiotaProcess: A comprehensive R package for deep mining microbiome
S Xu, L Zhan, W Tang, Q Wang, Z Dai, L Zhou, T Feng… - The Innovation, 2023 - cell.com
The data output from microbiome research is growing at an accelerating rate, yet mining the
data quickly and efficiently remains difficult. There is still a lack of an effective data structure …
data quickly and efficiently remains difficult. There is still a lack of an effective data structure …
Interfacing Seurat with the R tidy universe
Motivation Seurat is one of the most popular software suites for the analysis of single-cell
RNA sequencing data. Considering the popularity of the tidyverse ecosystem, which offers a …
RNA sequencing data. Considering the popularity of the tidyverse ecosystem, which offers a …
sccomp: Robust differential composition and variability analysis for single-cell data
S Mangiola, AJ Roth-Schulze… - Proceedings of the …, 2023 - National Acad Sciences
Cellular omics such as single-cell genomics, proteomics, and microbiomics allow the
characterization of tissue and microbial community composition, which can be compared …
characterization of tissue and microbial community composition, which can be compared …
The tidyomics ecosystem: Enhancing omic data analyses
WJ Hutchison, TJ Keyes, Tidyomics Consortium… - Nature …, 2024 - nature.com
The growth of omic data presents evolving challenges in data manipulation, analysis and
integration. Addressing these challenges, Bioconductor provides an extensive community …
integration. Addressing these challenges, Bioconductor provides an extensive community …
[HTML][HTML] A transcriptional signature of PDGF-DD activated natural killer cells predicts more favorable prognosis in low-grade glioma
Y Sun, AJ Sedgwick, Y Palarasah, S Mangiola… - Frontiers in …, 2021 - frontiersin.org
The binding of platelet-derived growth factor D (PDGF-DD) to the NKp44 receptor activates a
distinct transcriptional program in primary IL-2 expanded human natural killer (NK) cells. We …
distinct transcriptional program in primary IL-2 expanded human natural killer (NK) cells. We …
[HTML][HTML] Identification of early gene expression profiles associated with long-lasting antibody responses to the Ebola vaccine Ad26. ZEBOV/MVA-BN-Filo
F Blengio, H Hocini, L Richert, C Lefebvre, M Durand… - Cell Reports, 2023 - cell.com
Ebola virus disease is a severe hemorrhagic fever with a high fatality rate. We investigate
transcriptome profiles at 3 h, 1 day, and 7 days after vaccination with Ad26. ZEBOV and MVA …
transcriptome profiles at 3 h, 1 day, and 7 days after vaccination with Ad26. ZEBOV and MVA …
[HTML][HTML] A transcriptional signature of IL-2 expanded natural killer cells predicts more favorable prognosis in bladder cancer
Y Sun, AJ Sedgwick, MAAK Khan, Y Palarasah… - Frontiers in …, 2021 - frontiersin.org
Activation of natural killer (NK) cell function is regulated by cytokines, such as IL-2, and
secreted factors upregulated in the tumor microenvironment, such as platelet-derived growth …
secreted factors upregulated in the tumor microenvironment, such as platelet-derived growth …
TFIIS is crucial during early transcript elongation for transcriptional reprogramming in response to heat stress
S Obermeyer, R Stöckl, T Schnekenburger… - Journal of Molecular …, 2023 - Elsevier
In addition to the stage of transcriptional initiation, the production of mRNAs is regulated
during elongation. Accordingly, the synthesis of mRNAs by RNA polymerase II (RNAPII) in …
during elongation. Accordingly, the synthesis of mRNAs by RNA polymerase II (RNAPII) in …
MicrobiotaProcess: A comprehensive R package for managing and analyzing microbiome and other ecological data within the tidy framework
S Xu, Z Li, W Tang, Z Dai, L Zhou, T Feng, M Chen… - 2022 - researchsquare.com
The data output from microbiome research is growing at an accelerating rate, yet mining the
data quickly and efficiently remains difficult. There is still a lack of effective data structure to …
data quickly and efficiently remains difficult. There is still a lack of effective data structure to …