Molecular pharmacology of inflammation: Medicinal plants as anti-inflammatory agents
S Tasneem, B Liu, B Li, MI Choudhary… - Pharmacological research, 2019 - Elsevier
Except for an essential step for the pathology of multiple diseases including atherosclerosis
and rheumatoid arthritis, inflammation is an imperative therapeutic target for developing …
and rheumatoid arthritis, inflammation is an imperative therapeutic target for developing …
International Union of Basic and Clinical Pharmacology. LXXXIX. Update on the extended family of chemokine receptors and introducing a new nomenclature for …
F Bachelerie, A Ben-Baruch, AM Burkhardt… - Pharmacological …, 2014 - Elsevier
Sixteen years ago, the Nomenclature Committee of the International Union of Pharmacology
approved a system for naming human seven-transmembrane (7TM) G protein-coupled …
approved a system for naming human seven-transmembrane (7TM) G protein-coupled …
T helper 1 immunity requires complement-driven NLRP3 inflammasome activity in CD4+ T cells
INTRODUCTION The inflammasomes and the complement system are traditionally viewed
as quintessential components of innate immunity required for the detection and elimination …
as quintessential components of innate immunity required for the detection and elimination …
The complement system
JV Sarma, PA Ward - Cell and tissue research, 2011 - Springer
The complement system consists of a tightly regulated network of proteins that play an
important role in host defense and inflammation. Complement activation results in …
important role in host defense and inflammation. Complement activation results in …
Complement regulators and inhibitory proteins
PF Zipfel, C Skerka - Nature Reviews Immunology, 2009 - nature.com
The complement system is important for cellular integrity and tissue homeostasis.
Complement activation mediates the removal of microorganisms and the clearance of …
Complement activation mediates the removal of microorganisms and the clearance of …
The Concise Guide to PHARMACOLOGY 2013/14: G protein‐coupled receptors
SPH Alexander, HE Benson… - British journal of …, 2013 - Wiley Online Library
Abstract The Concise Guide to PHARMACOLOGY 2013/14 provides concise overviews of
the key properties of over 2000 human drug targets with their pharmacology, plus links to an …
the key properties of over 2000 human drug targets with their pharmacology, plus links to an …
The role of the anaphylatoxins in health and disease
A Klos, AJ Tenner, KO Johswich, RR Ager, ES Reis… - Molecular …, 2009 - Elsevier
The anaphylatoxin (AT) C3a, C5a and C5a-desArg are generally considered pro-
inflammatory polypeptides generated after proteolytic cleavage of C3 and C5 in response to …
inflammatory polypeptides generated after proteolytic cleavage of C3 and C5 in response to …
Interactions between coagulation and complement—their role in inflammation
K Oikonomopoulou, D Ricklin, PA Ward… - Seminars in …, 2012 - Springer
The parallel expression of activation products of the coagulation, fibrinolysis, and
complement systems has long been observed in both clinical and experimental settings …
complement systems has long been observed in both clinical and experimental settings …
C5a receptor (CD88) blockade protects against MPO-ANCA GN
H Xiao, DJ Dairaghi, JP Powers, LS Ertl… - Journal of the …, 2014 - journals.lww.com
Necrotizing and crescentic GN (NCGN) with a paucity of glomerular immunoglobulin
deposits is associated with ANCA. The most common ANCA target antigens are …
deposits is associated with ANCA. The most common ANCA target antigens are …
Mechanism of activation and biased signaling in complement receptor C5aR1
The complement system plays an important role in the innate immune response to invading
pathogens. The complement fragment C5a is one of its important effector components and …
pathogens. The complement fragment C5a is one of its important effector components and …