Osteoarthritis (OA) is one of the most prevalent chronic joint diseases worldwide, which
causes a series of problems, such as joint pain, muscle atrophy, and joint deformities …

γ-Butyrolactone, a five-membered lactone moiety, is one of the privileged structures of
diverse natural products and biologically active small molecules. Because of their broad …

The objective was to investigate the effect of kinsenoside (Kin) treatments on macrophage
polarity and evaluate the resulting protection of chondrocytes to attenuate osteoarthritis (OA) …

Kinsenoside (KD) exhibits anti-inflammatory and immunosuppressive effects. Dendritic cells
(DCs) are critical regulators of the pathologic inflammatory milieu in liver fibrosis (LF) …

Background Non-alcoholic steatohepatitis (NASH) has replaced viral hepatitis as the main
driver of the rising morbidity and mortality associated with cirrhosis and liver cancer …

Extensive research has implicated inflammation and oxidative stress in the development of
multiple diseases, such as diabetes, hepatitis, and arthritis. Kinsenoside (KD), a bioactive …

Background: Anoectochilus roxburghii (Orchidaceae) is a traditional Chinese medicinal herb
with anti-inflammatory, antilipemic, liver protective, immunomodulatory, and other …

The primary by-product of saffron (Crocus sativus) processing is saffron petals, which are
produced in large quantities but are discarded. The saffron petals contain a variety of …

Background Autoimmune hepatitis (AIH) is mediated by a cascade of T cell-mediated events
directed at liver cells and persistent inflammation within the liver can eventually result in liver …

An ischemic stroke usually causes blood-brain barrier (BBB) damage and excessive
oxidative stress (OS) levels. Kinsenoside (KD), a major effective compound extracted in …