Gallbladder cancer

JC Roa, P García, VK Kapoor, SK Maithel… - Nature reviews Disease …, 2022 - nature.com
Gallbladder cancer (GBC) is the most common cancer of the biliary tract, characterized by a
very poor prognosis when diagnosed at advanced stages owing to its aggressive behaviour …

[HTML][HTML] Gallbladder cancer epidemiology, pathogenesis and molecular genetics: Recent update

A Sharma, KL Sharma, A Gupta, A Yadav… - World journal of …, 2017 - ncbi.nlm.nih.gov
Gallbladder cancer is a malignancy of biliary tract which is infrequent in developed countries
but common in some specific geographical regions of developing countries. Late diagnosis …

miRNAs orchestration of gallbladder cancer-Particular emphasis on diagnosis, progression and drug resistance

RK Shahin, MA Elkady, AI Abulsoud… - … -Research and Practice, 2023 - Elsevier
Gallbladder cancer (GBC) is characterized by a highly invasive nature and a poor prognosis,
with adenocarcinoma being the main histological subtype. According to statistical data …

Overview of current targeted therapy in gallbladder cancer

X Song, Y Hu, Y Li, R Shao, F Liu, Y Liu - Signal Transduction and …, 2020 - nature.com
Gallbladder cancer (GBC) is rare, but is the most malignant type of biliary tract tumor.
Unfortunately, only a small population of cancer patients is acceptable for the surgical …

Gallbladder cancer: current multimodality treatment concepts and future directions

N Sturm, JS Schuhbaur, F Hüttner, L Perkhofer… - Cancers, 2022 - mdpi.com
Simple Summary Gallbladder cancer is the most common malignancy of the biliary tract and
is associated with several risk factors such as female sex, ethnic background, and chronic …

Genomic characterization of co-existing neoplasia and carcinoma lesions reveals distinct evolutionary paths of gallbladder cancer

J Lin, X Peng, K Dong, J Long, X Guo, H Li… - Nature …, 2021 - nature.com
Gallbladder carcinoma is the most common cancer of the biliary tract with dismal survival
largely due to delayed diagnosis. Biliary tract intraepithelial neoplasia (BilIN) is the common …

UCP2 promotes proliferation and chemoresistance through regulating the NF-κB/β-catenin axis and mitochondrial ROS in gallbladder cancer

J Yu, L Shi, W Lin, B Lu, Y Zhao - Biochemical pharmacology, 2020 - Elsevier
Abstract Uncoupling protein 2 (UCP2) is a mitochondrial anion carrier which plays a key role
in energy homeostasis. UCP2 is deregulated in several human cancers and has been …

Evolving paradigms in the systemic treatment of advanced gallbladder cancer: updates in year 2022

ZI Hu, KH Lim - Cancers, 2022 - mdpi.com
Simple Summary Gallbladder cancer is distinct type of biliart tract cancer that is rare,
aggressive and with limited treatment options aside from surgical resection. As of now in …

[HTML][HTML] Somatic genetic aberrations in gallbladder cancer: comparison between Chinese and US patients

P Yang, M Javle, F Pang, W Zhao… - … surgery and nutrition, 2019 - ncbi.nlm.nih.gov
Background Gallbladder cancer (GBC) is often diagnosed at an advanced stage with limited
therapeutic options and poor prognosis. The five-year survival rate of this cancer when …

Targeting specific molecular pathways holds promise for advanced gallbladder cancer therapy

C Bizama, P García, JA Espinoza, H Weber… - Cancer Treatment …, 2015 - Elsevier
Gallbladder cancer is the most common and aggressive malignancy of the biliary tract. The
complete surgical resection is the only potentially curative approach in early stage; however …