Cytoskeletal remodeling in cancer
J Aseervatham - Biology, 2020 - mdpi.com
Simple Summary Cell migration is an essential process from embryogenesis to cell death.
This is tightly regulated by numerous proteins that help in proper functioning of the cell. In …
This is tightly regulated by numerous proteins that help in proper functioning of the cell. In …
Structure, regulation and related diseases of the actin-binding protein gelsolin
J Feldt, M Schicht, F Garreis, J Welss… - Expert reviews in …, 2018 - cambridge.org
Gelsolin (GSN), one of the most abundant actin-binding proteins, is involved in cell motility,
shape and metabolism. As a member of the GSN superfamily, GSN is a highly structured …
shape and metabolism. As a member of the GSN superfamily, GSN is a highly structured …
[HTML][HTML] Quantitative proteomic analysis of the metastasis-inhibitory mechanism of miR-193a-3p in non-small cell lung cancer
W Deng, M Yan, T Yu, H Ge, H Lin, J Li, Y Liu… - Cellular Physiology and …, 2015 - karger.com
Background: microRNAs can repress the expression of target genes by destabilizing their
mRNAs or by inhibiting their translation. Our previous findings suggested that miR-193a-3p …
mRNAs or by inhibiting their translation. Our previous findings suggested that miR-193a-3p …
[HTML][HTML] Proteomics and its applications in breast cancer
Breast cancer is an individually unique, multi-faceted and chameleonic disease, an eternal
challenge for the new era of high-integrated precision diagnostic and personalized …
challenge for the new era of high-integrated precision diagnostic and personalized …
Urinary proteome alterations in HER2 enriched breast cancer revealed by multipronged quantitative proteomics
Globally, breast cancer is the second most common cancer among women. Although
biomarker discoveries through various proteomic approaches of tissue and serum samples …
biomarker discoveries through various proteomic approaches of tissue and serum samples …
Metastasis suppressors in breast cancers: mechanistic insights and clinical potential
For the most part, normal epithelial cells do not disseminate to other parts of the body and
proliferate, as do metastatic cells. Presumably, a class of molecules—termed metastasis …
proliferate, as do metastatic cells. Presumably, a class of molecules—termed metastasis …
Circulating proteins associated with response and resistance to neoadjuvant chemotherapy in HER2-positive breast cancer
MP Chantada-Vázquez, M Conde-Amboage… - Cancers, 2022 - mdpi.com
Simple Summary The goal of this study was to find circulating proteins that can be easily
sampled and incorporated into a clinical setting to improve predictive treatment response in …
sampled and incorporated into a clinical setting to improve predictive treatment response in …
Computational identification of multi-omic correlates of anticancer therapeutic response
LC Stetson, T Pearl, Y Chen, JS Barnholtz-Sloan - BMC genomics, 2014 - Springer
Background A challenge in precision medicine is the transformation of genomic data into
knowledge that can be used to stratify patients into treatment groups based on predicted …
knowledge that can be used to stratify patients into treatment groups based on predicted …
Gelsolin is associated with longer metastasis-free survival and reduced cell migration in estrogen receptor-positive breast cancer
AM Stock, F Klee, K Edlund, M Grinberg… - Anticancer …, 2015 - ar.iiarjournals.org
Background: Tumor cell migration is a prerequisite for metastasis formation. The role of the
actin-modulating protein, gelsolin, in metastasis is controversial, as previous studies have …
actin-modulating protein, gelsolin, in metastasis is controversial, as previous studies have …
Quantitative tissue proteomic investigation of invasive ductal carcinoma of breast with luminal B HER2 positive and HER2 enriched subtypes towards potential …
N Pendharkar, A Gajbhiye, K Taunk… - Journal of …, 2016 - Elsevier
Worldwide, breast cancer is one of the frequently diagnosed cancers in women with high
mortality if not diagnosed at early stage. Although biomarker discoveries through various …
mortality if not diagnosed at early stage. Although biomarker discoveries through various …