Coenzyme Q (CoQ) is a remarkably hydrophobic, redox-active lipid that empowers diverse
cellular processes. Although most known for shuttling electrons between mitochondrial …

Distinct morphologies of the mitochondrial network support divergent metabolic and
regulatory processes that determine cell function and fate,–. The mechanochemical GTPase …

Originally identified as a key component of the mitochondrial respiratory chain, Coenzyme Q
(CoQ or CoQ10 for human tissues) has recently been revealed to be essential for many …

Coenzyme Q (CoQ) is a redox lipid that fulfills critical functions in cellular bioenergetics and
homeostasis. CoQ is synthesized by a multi-step pathway that involves several COQ …

Distal hereditary motor neuropathy represents a group of motor inherited neuropathies
leading to distal weakness. We report a family of two brothers and a sister affected by distal …

Abstract Primary coenzyme Q10 (CoQ 10) deficiency is a group of inborn errors of
metabolism caused by defects in CoQ 10 biosynthesis. Biallelic pathogenic variants in …

It was with great interest that we read the article published by Jacquier et al. 1 regarding
autosomal recessive distal hereditary motor neuropathy (dHMN) caused by a pathogenic …

The protein encoded by COQ7 is required for CoQ10 synthesis in humans, hydroxylating 3‐
demethoxyubiquinol (DMQ10) in the second to last steps of the pathway. COQ7 mutations …

Coenzyme Q (Q) is a key lipid electron transporter, but several aspects of its biosynthesis
and redox homeostasis remain undefined. Various flavoproteins reduce ubiquinone …

Mitochondria are complex organelles that play a central role in metabolism. Dynamic
membrane-associated processes regulate mitochondrial morphology and bioenergetics in …