Opportunities for Therapeutic Modulation of O-GlcNAc
SS Cheng, AC Mody, CM Woo - Chemical Reviews, 2024 - ACS Publications
O-Linked β-N-acetylglucosamine (O-GlcNAc) is an essential, dynamic monosaccharide post-
translational modification (PTM) found on serine and threonine residues of thousands of …
translational modification (PTM) found on serine and threonine residues of thousands of …
The non-catalytic domains of O-GlcNAc cycling enzymes present new opportunities for function-specific control
O-GlcNAcylation is an essential protein glycosylation governed by two O-GlcNAc cycling
enzymes: O-GlcNAc transferase (OGT) installs a single sugar moiety N-acetylglucosamine …
enzymes: O-GlcNAc transferase (OGT) installs a single sugar moiety N-acetylglucosamine …
Enrichment of cancer stem cell subpopulation alters the glycogene expression profile of colorectal cancer cells
J de Andrade-da-Costa, M de-Souza-Ferreira… - Discover Oncology, 2024 - Springer
Colorectal cancer (CRC) has a high mortality rate, resulting from the processes of metastasis
and disease recurrence. Cancer stem cells (CSCs) are believed to be crucial for both …
and disease recurrence. Cancer stem cells (CSCs) are believed to be crucial for both …