Dopamine: functions, signaling, and association with neurological diseases
The dopaminergic system plays important roles in neuromodulation, such as motor control,
motivation, reward, cognitive function, maternal, and reproductive behaviors. Dopamine is a …
motivation, reward, cognitive function, maternal, and reproductive behaviors. Dopamine is a …
Motor and non-motor circuit disturbances in early Parkinson disease: which happens first?
For the last two decades, pathogenic concepts in Parkinson disease (PD) have revolved
around the toxicity and spread of α-synuclein. Thus, α-synuclein would follow caudo-rostral …
around the toxicity and spread of α-synuclein. Thus, α-synuclein would follow caudo-rostral …
The neural network of motor imagery: an ALE meta-analysis
Motor imagery (MI) or the mental simulation of action is now increasingly being studied
using neuroimaging techniques such as positron emission tomography and functional …
using neuroimaging techniques such as positron emission tomography and functional …
Goal-directed and habitual control in the basal ganglia: implications for Parkinson's disease
P Redgrave, M Rodriguez, Y Smith… - Nature Reviews …, 2010 - nature.com
Progressive loss of the ascending dopaminergic projection in the basal ganglia is a
fundamental pathological feature of Parkinson's disease. Studies in animals and humans …
fundamental pathological feature of Parkinson's disease. Studies in animals and humans …
Microglia response during Parkinson's disease: alpha-synuclein intervention
SA Ferreira, M Romero-Ramos - Frontiers in cellular neuroscience, 2018 - frontiersin.org
The discovery of the central role played by the protein alpha-synuclein in Parkinson's
disease and other Lewy body brain disorders has had a great relevance in the …
disease and other Lewy body brain disorders has had a great relevance in the …
Efficacy and safety of deep brain stimulation in Tourette syndrome: the international Tourette syndrome deep brain stimulation public database and registry
D Martinez-Ramirez, J Jimenez-Shahed… - JAMA …, 2018 - jamanetwork.com
Importance Collective evidence has strongly suggested that deep brain stimulation (DBS) is
a promising therapy for Tourette syndrome. Objective To assess the efficacy and safety of …
a promising therapy for Tourette syndrome. Objective To assess the efficacy and safety of …
The scientific and clinical basis for the treatment of Parkinson disease (2009)
CW Olanow, MB Stern, K Sethi - Neurology, 2009 - AAN Enterprises
Parkinson disease (PD) is an age-related neurodegenerative disorder that affects as many
as 1–2% of persons aged 60 years and older. With the aging of the population, the …
as 1–2% of persons aged 60 years and older. With the aging of the population, the …
Neuropathology of sporadic Parkinson's disease: evaluation and changes of concepts
KA Jellinger - Movement disorders, 2012 - Wiley Online Library
Abstract Parkinson's disease (PD), one of the most frequent neurodegenerative disorders, is
no longer considered a complex motor disorder characterized by extrapyramidal symptoms …
no longer considered a complex motor disorder characterized by extrapyramidal symptoms …
Compensatory mechanisms in Parkinson's disease: circuits adaptations and role in disease modification
The motor features of Parkinson's disease (PD) are well known to manifest only when striatal
dopaminergic deficit reaches 60–70%. Thus, PD has a long pre-symptomatic and pre-motor …
dopaminergic deficit reaches 60–70%. Thus, PD has a long pre-symptomatic and pre-motor …
The brainstem pathologies of Parkinson's disease and dementia with Lewy bodies
Parkinson's disease (PD) and dementia with L ewy bodies (DLB) are among the human
synucleinopathies, which show alpha‐synuclein immunoreactive neuronal and/or glial …
synucleinopathies, which show alpha‐synuclein immunoreactive neuronal and/or glial …