Triple‑negative breast cancer (TNBC) accounts for 10‑15% of all breast cancer cases.
TNBCs lack estrogen and progesterone receptors and express low levels of HER2, and …

Background: Characterization of the epigenome is a primary interest for children's
environmental health researchers studying the environmental influences on human …

Breast tumors of the basal-like, hormone receptor–negative subtype remain an unmet
clinical challenge, as there is high rate of recurrence and poor survival in patients following …

Ets1 belongs to the large family of the ETS domain family of transcription factors and is
involved in cancer progression. In most carcinomas, Ets1 expression is linked to poor …

Breast cancer is now globally the most frequent cancer and leading cause of women's
death. Two thirds of breast cancers express the luminal estrogen receptor-positive (ERα+) …

Simple Summary Factors such as estrogen, progesterone, and androgen receptors, also
known as nuclear receptors, are abundantly expressed in the majority of breast cancers …

Although new developments of surgery, chemotherapy, radiotherapy, and immunotherapy
treatments for cancer have improved patient survival, the emergence of chemoresistance in …

Snail1, a key transcription factor of epithelial–mesenchymal transition (EMT), is subjected to
ubiquitination and degradation, but the mechanism by which Snail1 is stabilized in tumours …

Chromosome 17q gains are almost invariably present in high-risk neuroblastoma cases.
Here, we perform an integrative epigenomics search for dosage-sensitive transcription …

In this review, we will discuss how the cell of origin may modulate breast cancer intratumoral
heterogeneity (ITH) as well as the role of ITH in the evolution of cancer. The clonal evolution …