In recent years, the study of lymphangiogenesis and fibrotic diseases has made
considerable achievements, and accumulating evidence indicates that lymphangiogenesis …

Acute kidney injury (AKI) is a common and serious disease entity that affects native kidneys
and allografts but for which no specific treatments exist. Complex intrarenal inflammatory …

Background While targeted systemic inflammatory modulators show promise in preventing
chronic kidney disease (CKD) progression, the causal link between specific inflammatory …

As an integral part of the vascular system, the lymphatic vasculature is essential for tissue
fluid homeostasis, nutritional lipid assimilation and immune regulation. The composition of …

Abstract Purpose of Review Kidney disease is a strong modulator of the composition and
metabolism of the intestinal microbiome that produces toxins and inflammatory factors. The …

Kidney disease is associated with adverse consequences in many organs beyond the
kidney, including the heart, lungs, brain, and intestines. The kidney-intestinal cross talk …

Objective Acute kidney injury (AKI) is a clinical syndrome that occurs as a result of a
dramatic decline in kidney function caused by a variety of etiological factors. Its main …

This study aimed to explore the mechanism of Xiaoyu Xiezhuo decoction (XXD) on ischemia–
reperfusion-induced acute kidney injury (IRI-AKI) using network pharmacology methods and …

BACKGROUND: Lymphatic collecting vessels in the kidney are critical in clearing interstitial
fluid, macromolecules, and infiltrating immune cells. Dysfunction of the lymphatic vessels …

Lipoprotein modification by reactive dicarbonyls, including isolevuglandin (IsoLG), produces
dysfunctional particles. Kidneys participate in lipoprotein metabolism, including tubular …