Coiled-coil-helix-coiled-coil-helix domain containing 2 (CHCHD2) and Coiled-coil-helix-
coiled-coil-helix domain containing 10 (CHCHD10) are mitochondrial proteins that are …

In the last decade, dominant mutations in the mitochondrial protein CHCHD10 (p. R15L and
p. S59L) and its paralog CHCHD2 (p. T61I) were shown to cause familial amyotrophic lateral …

Mutations in CHCHD10, a mitochondrial protein with undefined functions, are associated
with autosomal dominant mitochondrial diseases. Chchd10 knock-in mice harboring a …

Abstract TAR DNA-binding protein 43 (TDP-43) is a versatile RNA/DNA-binding protein with
multifaceted processes. While TDP-43 has been extensively studied in the context of …

Background Pulmonary arterial hypertension (PAH) is a highly prevalent cardiopulmonary
disorder characterized by vascular remodeling and increased resistance in pulmonary …

Mutations in CHCHD10 and CHCHD2, encoding two paralogous mitochondrial proteins,
have been identified in cases of amyotrophic lateral sclerosis, frontotemporal lobar …

Purpose: The objective of this research was to examine the causal link between PCOS and
plasma mitochondrial coiled-coil-helix-coiled-coil-helix domain (CHCHD) proteins using a …

The mitochondria are responsible for producing energy within the cell, and in mitochondrial
myopathy, there is a defect in the energy production process. The CHCHD10 gene codes for …

In the last decade, dominant mutations in the mitochondrial protein CHCHD10 and its
paralogue CHCHD2 were shown to cause familial amyotrophic lateral sclerosis and …

Les paralogues mitochondriaux CHCHD10 et CHCHD2 sont associés à plusieurs maladies
neurodégénératives, notamment la sclérose latérale amyotrophique (SLA) et la maladie de …