Delivery of cancer therapeutics to extracellular and intracellular targets: Determinants, barriers, challenges and opportunities

JLS Au, BZ Yeung, MG Wientjes, Z Lu… - Advanced drug delivery …, 2016 - Elsevier
Advances in molecular medicine have led to identification of worthy cellular and molecular
targets located in extracellular and intracellular compartments. Effectiveness of cancer …

Prostate cancer research: the next generation; report from the 2019 Coffey‐Holden prostate cancer academy meeting

AK Miyahira, A Sharp, L Ellis, J Jones, S Kaochar… - The …, 2020 - Wiley Online Library
Abstract Introduction The 2019 Coffey‐Holden Prostate Cancer Academy (CHPCA)
Meeting,“Prostate Cancer Research: The Next Generation,” was held 20 to 23 June, 2019, in …

[HTML][HTML] CD44 is a potential immunotherapeutic target and affects macrophage infiltration leading to poor prognosis

S Liu, Z Liu, A Shang, J Xun, Z Lv, S Zhou, C Liu… - Scientific Reports, 2023 - nature.com
CD44 plays a key role in the communication of CSCs with the microenvironment and the
regulation of stem cell properties. UALCAN was used to analyze the expression of CD44 in …

STAT3 inhibition combined with CpG immunostimulation activates antitumor immunity to eradicate genetically distinct castration-resistant prostate cancers

D Moreira, T Adamus, X Zhao, YL Su, Z Zhang… - Clinical Cancer …, 2018 - AACR
Purpose: Prostate cancers show remarkable resistance to emerging immunotherapies,
partly due to tolerogenic STAT3 signaling in tumor-associated myeloid cells. Here, we …

Tumor cell heterogeneity and resistance; report from the 2018 Coffey‐Holden Prostate Cancer Academy Meeting

AK Miyahira, RB Den, MI Carlo, R De Leeuw… - The …, 2019 - Wiley Online Library
Introduction The 2018 Coffey‐Holden Prostate Cancer Academy (CHPCA) Meeting,“Tumor
Cell Heterogeneity and Resistance,” was held in Los Angeles, California from June 21 to 24 …

Disrupting prostate cancer research: Challenge accepted; report from the 2023 Coffey‐Holden Prostate Cancer Academy Meeting

AK Miyahira, SC Kamran, T Jamaspishvili… - The …, 2024 - Wiley Online Library
Abstract Introduction The 2023 Coffey‐Holden Prostate Cancer Academy (CHPCA) Meeting,
themed “Disrupting Prostate Cancer Research: Challenge Accepted,” was convened at the …

Exploring new frontiers in prostate cancer research: Report from the 2022 Coffey− Holden prostate cancer academy meeting

AK Miyahira, JE Hawley, R Adelaiye‐Ogala… - The …, 2023 - Wiley Online Library
Abstract Introduction The 2022 Coffey− Holden Prostate Cancer Academy (CHPCA)
Meeting,“Exploring New Frontiers in Prostate Cancer Research,” was held from June 23 to …

Multidisciplinary intervention of early, lethal metastatic prostate cancer: Report from the 2015 Coffey‐Holden Prostate Cancer Academy Meeting

AK Miyahira, JM Lang, RB Den, IP Garraway… - The …, 2016 - Wiley Online Library
Background The 2015 Coffey‐Holden Prostate Cancer Academy Meeting, themed:“
Multidisciplinary Intervention of Early, Lethal Metastatic Prostate Cancer,” was held in La …

Prostate cancer research in the 21st century; report from the 2021 Coffey‐Holden prostate cancer academy meeting

AK Miyahira, JC Zarif, CC Coombs, RR Flavell… - The …, 2022 - Wiley Online Library
Abstract Introduction The 2021 Coffey‐Holden Prostate Cancer Academy (CHPCA)
Meeting,“Prostate Cancer Research in the 21st Century,” was held virtually, from June 24 …

[HTML][HTML] The relationship between obesity, prostate tumor infiltrating lymphocytes and macrophages, and biochemical failure

C Zeigler-Johnson, KH Morales, P Lal, M Feldman - PLoS One, 2016 - journals.plos.org
Background Obesity reflects a chronic inflammatory environment that may contribute to
prostate cancer progression and poor treatment outcomes. However, it is not clear which …