Translational bioinformatics for human reproductive biology research: examples, opportunities and challenges for a future reproductive medicine

K Liu, Y Zhang, C Martin, X Ma, B Shen - International Journal of …, 2022 - mdpi.com
Since 1978, with the first IVF (in vitro fertilization) baby birth in Manchester (England), more
than eight million IVF babies have been born throughout the world, and many new …

piRNAs and PIWI proteins as diagnostic and prognostic markers of genitourinary cancers

K Hanusek, S Poletajew, P Kryst… - Biomolecules, 2022 - mdpi.com
piRNAs (PIWI-interacting RNAs) are small non-coding RNAs capable of regulation of
transposon and gene expression. piRNAs utilise multiple mechanisms to affect gene …

A three‐gene DNA methylation biomarker accurately classifies early stage prostate cancer

PG Patel, T Wessel, A Kawashima, JBA Okello… - The …, 2019 - Wiley Online Library
Background We identify and validate accurate diagnostic biomarkers for prostate cancer
through a systematic evaluation of DNA methylation alterations. Materials and methods We …

A critical appraisal of biomarkers in prostate cancer

VM Narayan - World journal of urology, 2020 - Springer
Purpose A number of urine and blood-based biomarker tests have been described for
prostate cancer, although to date there has only been a limited exploration of the …

Clinical significance of the Lacdi NA c‐glycosylated prostate‐specific antigen assay for prostate cancer detection

T Yoneyama, Y Tobisawa, T Kaneko, T Kaya… - Cancer …, 2019 - Wiley Online Library
To reduce unnecessary prostate biopsies (Pbx), better discrimination is needed. To identify
clinically significant prostate cancer (CSPC) we determined the performance of Lacdi NA c …

Prostate cancer screening: Continued controversies and novel biomarker advancements

A Tidd-Johnson, SA Sebastian, M Afaq… - Current …, 2022 - journals.lww.com
Prostate cancer (PCa) screening remains one of the most controversial topics in clinical and
public health. Despite being the second most common cancer in men worldwide …

Expression of AR-V7 (Androgen Receptor Variant 7) Protein in granular cytoplasmic structures is an independent prognostic factor in prostate cancer patients

P König, M Eckstein, R Jung, A Abdulrahman… - Cancers, 2020 - mdpi.com
Simple Summary The expression of the androgen receptor (AR) and its splice variant AR-V7
is crucial for prostate cancer (PCa) biology. An immunohistochemical staining was …

Expression of GP88 (Progranulin) protein is an independent prognostic factor in prostate cancer patients

A Abdulrahman, M Eckstein, R Jung, J Guzman… - Cancers, 2019 - mdpi.com
Prostate cancer, the second most common cancer, is still a major cause of morbidity and
mortality among men worldwide. The expression of the survival and proliferation factor …

[HTML][HTML] Using prostatic fluid levels of zinc to bromine concentration ratio in non-invasive and highly accurate screening for prostate cancer

V Zaichick, S Zaichick - Journal of Hematalogy and …, 2019 - ijn-medicalarticles.info
Prostate specific antigen (PSA) does not provide the high reliability and precision that is
required for an accurate screening for prostate cancer (PCa). The aim of our study was to …

How should radiologists incorporate non-imaging prostate cancer biomarkers into daily practice?

P Rajwa, J Syed, MS Leapman - Abdominal Radiology, 2020 - Springer
Objective To review the current body of evidence surrounding non-imaging biomarkers in
patients with known or suspected prostate cancer. Results Several non-imaging biomarkers …