The global burden of hypertension is rising and accounts for substantial morbidity and
mortality. Lifestyle factors such as diet and physical inactivity contribute to this burden …

Exercise has a myriad of physiological benefits that derive in part from its ability to improve
cardiometabolic health. The periodic metabolic stress imposed by regular exercise appears …

The heart is a remarkably adaptive organ, capable of increasing its minute output and
overcoming short-term or prolonged pressure overload. The structural response, in addition …

The aim of the present study was to verify the effects of low-intensity endurance training and
detraining on the mechanical and molecular properties of cardiomyocytes from …

We have previously reported chronic low-intensity interval exercise training attenuates
fibrosis, impaired cardiac mitochondrial function, and coronary vascular dysfunction in …

Cardiotoxicity is a side effect for cancer patients treated with doxorubicin (DOX). We tested
the hypothesis that low-intensity aerobic exercise concomitant with DOX treatment would …

Objective To evaluate the effect of low-intensity chronic exercise training (ExT) on blood
pressure (BP), as well as the cardiac alterations associated with hypertension in aging …

Research has demonstrated that the high capacity requirements of the heart are satisfied by
a preference for oxidation of fatty acids. However, it is well known that a stressed heart, as in …

PURPOSE: To examine the effects of oxymatrine (OMT) on ventricular remodeling in
spontaneous hypertension rat (SHR) and the underlying mechanism. METHODS: SHRs …

Background: Regulation of intracellular calcium (Ca2+) in cardiomyocytes is altered by
hypertension; and aerobic exercise brings benefits to hypertensive individuals. Objective: To …