Regulatory T cells (Tregs) play a key role in maintaining immune balance and regulating the
loss of self-tolerance mechanisms in various autoimmune diseases, including primary …

Tertiary lymphoid structures (TLSs) are defined as lymphoid aggregates formed in non-
hematopoietic organs under pathological conditions. Similar to secondary lymphoid organs …

Sjögrens syndrome (SS) is caused by autoantibodies that attack proprioceptive salivary and
lacrimal gland tissues. Damage to the glands leads to dry mouth and eyes and affects …

Primary Sjögren's syndrome (pSS) is a highly heterogeneous disease in terms of clinical
presentation ranging from a mild disease localised to the salivary and lacrimal glands, to …

Tertiary lymphoid structures (TLSs) are organized aggregates of immune cells found in the
tumor microenvironment. TLS can influence primary hepatic carcinoma (PHC) occurrence …

Introduction Increased CCL5 expression and CD8 T cells have been shown to be pivotal
regulators of immunopathology in primary Sjögren's syndrome (pSS) and pSS-like disease …

原发性干燥综合征是一种由大量淋巴细胞浸润外分泌腺并导致腺体功能障碍的自身免疫性疾病,
其发病机制与遗传, 免疫缺陷和病毒感染等导致外分泌腺慢性炎症反应有关 …

Among all systemic autoimmune diseases, Sjögren's syndrome gathers some unique
clinical features that place the disease in the center of systemic autoimmunity and internal …

Innate lymphoid cells (ILCs), as newly discovered antigen-independent innate immune cells,
respond promptly to stimuli by secreting effector cytokines to exert effector functions similar …

Purpose Sjogren's Syndrome (SS) is a systemic autoimmune disease primarily
characterized by dysfunction of the exocrine glands. Research into the etiology and …