Clostridia comprise bacteria of environmental, biotechnological and medical interest and
many commensals of the gut microbiota. Because of their strictly anaerobic lifestyle, oxygen …

Proteins belonging to the FUR (ferric uptake regulator) family are the cornerstone of
metalloregulation in most prokaryotes. Although numerous reviews have been devoted to …

Microbial-driven nitrogen removal is a crucial step in modern full-scale wastewater treatment
plants (WWTPs), and the complexity of nitrogen transformation is integral to the various …

Significance: Iron is required for growth and is often redox active under cytosolic conditions.
As a result of its facile redox chemistry, iron homeostasis is intricately involved with oxidative …

Highlights•Low oxygen tensions are present throughout the gastrointestinal tract.•Although
Clostridioides difficile is considered as obligate anaerobe, this bacterium can tolerate low …

Clostridioides difficile, the major cause of antibiotic-associated diarrhea, is a strict anaerobic,
sporulating Firmicutes. However, during its infectious cycle, this anaerobe is exposed to low …

Summary FurC (PerR) from Anabaena sp. PCC7120 was previously described as a key
transcriptional regulator involved in setting off the oxidative stress response. In the last …

Metal and redox homeostasis in cyanobacteria is tightly controlled to preserve the
photosynthetic machinery from mismetallation and minimize cell damage. This control is …

Bacteria display an array of enzymes to detoxify reactive oxygen species that cause damage
to DNA and to other biomolecules leading to cell death. Hydrogen peroxide is one of these …

Peroxide sensing is essential for bacterial survival during aerobic metabolism and host
infection. Peroxide stress regulators (PerRs) are homodimeric transcriptional repressors with …