Over a century of scientific inquiry since the discovery of v-SRC but still no final judgement
on SRC function. However, a significant body of work has defined Src family kinases as key …

Tumor cells movement and migration are inseparable from the integrity of lipid rafts and the
formation of lamellipodia, and lipid rafts are also a prerequisite for the formation of …

Hematological cancers are a group of malignancies affecting human hematopoietic and
lymphoid tissues. Although the patients respond to treatment regimen during initial phases …

Purpose: The heterogeneity of tumor cells presents a major challenge to cancer diagnosis
and therapy. Cutaneous T-cell lymphomas (CTCL) are a group of T lymphocyte …

Studies have shown that cancer-associated fibroblasts (CAFs) play an irreplaceable role in
the occurrence and development of tumors. Therefore, exploring the action and mechanism …

Acute myeloid leukemia (AML) has a high rate of treatment failure due to increased
prevalence of therapy resistance. Mesenchymal stem cells (MSCs) in the leukemia …

Background Acute myeloid leukemia (AML) is a hematological malignancy that remains a
therapeutic challenge due to the high incidence of disease relapse. To better understand …

Context Curcumin, a polyphenolic compound extracted from the rhizome of the tropical plant
Curcuma longa L.(Zingiberaceae), has been considered as a cancer chemopreventive drug …

Extramedullary (EM) colonization is a rare complication of acute myeloid leukemia (AML),
occurring in about 10% of patients, but the processes underlying tissue invasion are not …

Hematopoietic stem cells (HSCs) are known for their ability to proliferate and self-renew,
thus being responsible for sustaining the hematopoietic system and residing in the bone …