Sesame (Sesamum indicum L.), of the Pedaliaceae family, is one of the first oil crops used in
humans. It is widely grown and has a mellow flavor and high nutritional value, making it very …

Background Cytokine storm is the exaggerated immune response often observed in viral
infections. It is also intimately linked with the progression of COVID-19 disease as well as …

Sesame is the oldest oilseed crop known to humanity, though it contributes a small share in
the global vegetable oil production. Sesame oil contains nutrients, including lignans …

The nuclear factor erythroid 2-related factor 2 (Nrf2)/antioxidant response element (ARE)
pathway is an important cell signaling mechanism in maintaining redox homeostasis in …

Abstract Background Arbutin (Ar) has anti-oxidative and anti-inflammatory activities.
However, the effects of Ar on lipopolysaccharide (LPS)-induced acute kidney injury (AKI) are …

Sesamin, a major lignin isolated from sesame (Sesamum indicum) seeds and sesame oil, is
known to possess antioxidant and anti-inflammatory properties. Several studies have …

Ethnopharmacological relevance Renal disease is a significant public health concern that
affects people all over the world. The main limitations of conventional therapy are the …

Plant lignans exhibit a wide range of biological activities, which makes them the research
objects of potential use as therapeutic agents. They provide diverse naturally-occurring …

Inflammation is associated with the development and progression of various disorders
including atherosclerosis, diabetes mellitus and cancer. Sesamin, a fat-soluble lignan …

Bronchial asthma poses a considerable burden on both individual patients and public
health. Sesamin is a natural lignan that relieves asthma. However, the potential regulatory …