The essential fatty acid alpha-linolenic acid (ALA) is present in high amounts in oils such as
flaxseed, soy, hemp, rapeseed, chia, and perilla, while stearidonic acid is abundant in …

A sedentary lifestyle is associated with overweight/obesity, which involves excessive fat
body accumulation, triggering structural and functional changes in tissues, organs, and body …

Palmitic acid (PA) is significantly increased in the hypothalamus of mice, when fed
chronically with a high-fat diet (HFD). PA impairs insulin signaling in hypothalamic neurons …

Menopause strongly increases incidence and consequences of obesity and non-
communicable diseases in women, with recent research suggesting a very early onset of …

A subset of genetic disorders termed ciliopathies are associated with obesity. The
mechanisms behind cilia dysfunction and altered energy homeostasis in these syndromes …

Pediatric obesity-related metabolic syndrome (MetS) and nonalcoholic fatty liver disease
(NAFLD) are increasingly frequent conditions with a still-elusive diagnosis and low-efficacy …

A variety of axes between brain and abdominal organs have been reported, but the
interaction between brain and visceral white adipose tissue (vWAT) remains unclear. In this …

Metabolic diseases such as obesity and type 2 diabetes in humans have been linked to
alterations in the gastrointestinal microbiota and metabolome. Knowledge of these …

Maternal overnutrition during pregnancy leads to metabolic alterations, including obesity,
hyperphagia, and inflammation in the offspring. Nutritional priming of central inflammation …

Background & aims Metabolically unhealthy overweight (MUO) individuals and
metabolically healthy overweight (MHO) individuals differ in biomarkers of atherogenesis …