Retina in a dish: Cell cultures, retinal explants and animal models for common diseases of the retina

S Schnichels, F Paquet-Durand, M Löscher… - Progress in retinal and …, 2021 - Elsevier
For many retinal diseases, including age-related macular degeneration (AMD), glaucoma,
and diabetic retinopathy (DR), the exact pathogenesis is still unclear. Moreover, the currently …

Main properties and current applications of some polysaccharides as biomaterials

M Rinaudo - Polymer international, 2008 - Wiley Online Library
This review concerns the applications of some polysaccharides in the domain of
biomaterials and bioactive polymers. Natural polysaccharides from different sources have …

[HTML][HTML] 3D culture of human pluripotent stem cells in RGD-alginate hydrogel improves retinal tissue development

NC Hunt, D Hallam, A Karimi, CB Mellough, J Chen… - Acta biomaterialia, 2017 - Elsevier
No treatments exist to effectively treat many retinal diseases. Retinal pigmented epithelium
(RPE) and neural retina can be generated from human embryonic stem cells/induced …

RPE transplantation and its role in retinal disease

L da Cruz, FK Chen, A Ahmado, J Greenwood… - Progress in retinal and …, 2007 - Elsevier
Retinal pigment epithelial (RPE) transplantation aims to restore the subretinal anatomy and
re-establish the critical interaction between the RPE and the photoreceptor, which is …

The application of biomaterials to tissue engineering neural retina and retinal pigment epithelium

NC Hunt, D Hallam, V Chichagova… - Advanced …, 2018 - Wiley Online Library
The prevalence of degenerative retinal disease is ever increasing as life expectancy rises
globally. The human retina fails to regenerate and the use of human embryonic stem cells …

[HTML][HTML] Retinoic acid-loaded alginate microspheres as a slow release drug delivery carrier for intravitreal treatment

F Wang, S He, B Chen - Biomedicine & Pharmacotherapy, 2018 - Elsevier
Pharmacotherapy were the mainstream methods for the treatment of proliferative
vitreoretinopathy (PVR), one of the leading causes of blindness. Due to the negligible side …

Prospectives for gene therapy of retinal degenerations

G Thumann - Current genomics, 2012 - ingentaconnect.com
Retinal degenerations encompass a large number of diseases in which the retina and
associated retinal pigment epithelial (RPE) cells progressively degenerate leading to severe …

Influence of carrier materials and coatings on retinal pigment epithelium cultivation and functions

P Dörschmann, S Böser, D Isik, C Arndt… - Experimental Eye …, 2022 - Elsevier
Abstract Properties of retinal pigment epithelium (RPE) are relevant for the development of
cell culture models concerning an exact reproduction of the ocular cell biology. Here, we …

海藻酸钠-维甲酸微球兔眼内注射病理学研究

王凤翔, 何守志, 李新建, 梁秋丽, 陈兵 - 国际眼科杂志, 2006 - cqvip.com
目的: 观察注射用海藻酸钠-维甲酸(alginate sodium-retinoicacid: AGS-RA)
微球缓释系统在玻璃体腔内的崩解过程. 方法: 有机溶剂将维甲酸溶解, 与15g/L …

Poly-N-isopropylacrylamide-based Thermoresponsive Hydrogels for Retinal Pigment Epithelial Cell Delivery

N Amaral - 2021 - macsphere.mcmaster.ca
Despite being the most prevalent presentation of Age-Related Macular Degeneration
(AMD), dry AMD (dAMD) lacks a therapeutic treatment. Retinal pigment epithelium (RPE) …