Basic principles and recent advances in magnetic cell separation

M Frenea-Robin, J Marchalot - Magnetochemistry, 2022 - mdpi.com
Magnetic cell separation has become a key methodology for the isolation of target cell
populations from biological suspensions, covering a wide spectrum of applications from …

Microfluidic applications of magnetic particles for biological analysis and catalysis

MAM Gijs, F Lacharme, U Lehmann - Chemical reviews, 2010 - ACS Publications
Since the introduction of the concept of Micro Total Analysis System or µTAS in 1990, 1 the
interest in and impact of such devices, also called lab-on-a-chip or miniaturized analysis …

Ultrahigh-throughput magnetic sorting of large blood volumes for epitope-agnostic isolation of circulating tumor cells

A Mishra, TD Dubash, JF Edd… - Proceedings of the …, 2020 - National Acad Sciences
Circulating tumor cell (CTC)-based liquid biopsies provide unique opportunities for cancer
diagnostics, treatment selection, and response monitoring, but even with advanced …

Magnetic levitation of single cells

NG Durmus, HC Tekin, S Guven… - Proceedings of the …, 2015 - National Acad Sciences
Several cellular events cause permanent or transient changes in inherent magnetic and
density properties of cells. Characterizing these changes in cell populations is crucial to …

Microfluidic devices for blood fractionation

HW Hou, AAS Bhagat, WC Lee, S Huang, J Han… - Micromachines, 2011 - mdpi.com
Blood, a complex biological fluid, comprises 45% cellular components suspended in protein
rich plasma. These different hematologic components perform distinct functions in vivo and …

An intravascular magnetic wire for the high-throughput retrieval of circulating tumour cells in vivo

O Vermesh, A Aalipour, TJ Ge, Y Saenz… - Nature biomedical …, 2018 - nature.com
The detection and analysis of rare blood biomarkers is necessary for early diagnosis of
cancer and to facilitate the development of tailored therapies. However, current methods for …

On-chip manipulation of continuous picoliter-volume superparamagnetic droplets using a magnetic force

K Zhang, Q Liang, S Ma, X Mu, P Hu, Y Wang, G Luo - Lab on a Chip, 2009 - pubs.rsc.org
A microfluidic device for generating monodisperse superparamagnetic droplets and rapidly
manipulating desired droplets into designated sub-microchannels by an external magnetic …

Cell manipulation with magnetic particles toward microfluidic cytometry

C Liu, T Stakenborg, S Peeters, L Lagae - Journal of Applied Physics, 2009 - pubs.aip.org
Magnetic particles have become a promising tool for nearly all major lab-on-a-chip (LOC)
applications, from sample capturing, purification, enrichment, transport to detection. For …

Investigation of a two‐step device implementing magnetophoresis and dielectrophoresis for separation of circulating tumor cells from blood cells

A Shamloo, A Yazdani… - Engineering in life …, 2020 - Wiley Online Library
Identifying tumor cells from a pool of other cells has always been an appealing topic for
different purposes. The objective of this study is to discriminate circulating tumor cells …

Dielectrophoretic separation of live and dead monocytes using 3D carbon-electrodes

Y Yildizhan, N Erdem, M Islam, R Martinez-Duarte… - Sensors, 2017 - mdpi.com
Blood has been the most reliable body fluid commonly used for the diagnosis of diseases.
Although there have been promising investigations for the development of novel lab-on-a …