Fatty acids and lipid mediators in inflammatory bowel disease: from mechanism to treatment

D Yan, S Ye, Y He, S Wang, Y Xiao, X Xiang… - Frontiers in …, 2023 - frontiersin.org
Inflammatory Bowel Disease (IBD) is a chronic, relapsing inflammatory disorder of the
gastrointestinal tract. Though the pathogenesis of IBD remains unclear, diet is increasingly …

[HTML][HTML] Antioxidant Therapy in Inflammatory Bowel Diseases: How Far Have We Come and How Close Are We?

LEMS Xavier, TCG Reis, ASP Martins, JCF Santos… - Antioxidants, 2024 - mdpi.com
Inflammatory bowel diseases (IBD) pose a growing public health challenge with unclear
etiology and limited efficacy of traditional pharmacological treatments. Alternative therapies …

Casuarina glauca branchlets' extract as a potential treatment for ulcerative colitis: chemical composition, in silico and in vivo studies

ME Mohamed, AM El-Shafae, E Fikry… - Frontiers in …, 2023 - frontiersin.org
Ulcerative colitis (UC) is an inflammatory bowel disease that is often resistant to current
treatment options, leading to a need for alternative therapies. Herbal products have shown …

Krill Oil and Its Bioactive Components as a Potential Therapy for Inflammatory Bowel Disease: Insights from In Vivo and In Vitro Studies

Y Liu, AM Robinson, XQ Su, K Nurgali - Biomolecules, 2024 - mdpi.com
Krill oil is extracted from krill, a small crustacean in the Antarctic Ocean. It has received
growing attention because of krill oil's unique properties and diverse health benefits. Recent …

Diosmin-loaded Lipid chitosan hybrid nanoparticles boost the anti-inflammatory, antioxidant, and protective effect against acetic acid-induced colitis in rodents

WE Abd El Hady, ME Abdelmageed… - Journal of Drug Delivery …, 2024 - Elsevier
Diosmin showed poor water solubility and decreased bioavailability. The current study aims
to repurpose diosmin-loaded nanoparticles (LCHNps) to provide an alternative for the cure …

Tiron ameliorates acetic acid-induced colitis in rats: Role of TGF-β/EGFR/PI3K/NF-κB signaling pathway

RN El Mahdy, MA Nader, MG Helal… - International …, 2024 - Elsevier
Background Ulcerative colitis (UC), an ongoing inflammatory disorder of the colon, is
marked by persistent mucosal surface irritation extending from the rectum to the near …

Protective effect of Dulaglutide, a GLP1 agonist, on acetic acid-induced ulcerative colitis in rats: involvement of GLP-1, TFF-3, and TGF-β/PI3K/NF-κB signaling …

RNE Mahdy, MA Nader, MG Helal… - Naunyn-Schmiedeberg's …, 2024 - Springer
A chronic inflammatory condition of the colon called ulcerative colitis (UC) is characterized
by mucosal surface irritation that extends from the rectum to the near proximal colon …

Rutin mitigates acetic acid-induced ulcerative colitis: novel coloprotective mechanism

IO Sherif, NH Al-Shaalan, WF Awadin - Toxicology Research, 2024 - academic.oup.com
Background Ulcerative colitis, an inflammatory bowel disease, is characterized by a status of
oxidative stress and inflammation. Rutin is a natural flavonoid with many pharmacological …

Anti-inflammatory activity of Ziziphus jujuba hydroalcoholic extract in acetic acid-induced ulcerative colitis model

S Bahrami, N Babaei… - … of Complementary and …, 2024 - degruyter.com
Objectives Ulcerative colitis (UC) is a common gastrointestinal (GI) disorder characterized by
chronic inflammation. Current treatments primarily focus on symptom management, but they …

Research advancements and perspectives of inflammatory bowel disease: A comprehensive review

J Bai, Y Wang, F Li, Y Wu, J Chen, M Li… - Science …, 2024 - journals.sagepub.com
Inflammatory bowel disease (IBD) is a chronic inflammatory disease with increasing
incidence, such as Crohn's disease and ulcerative colitis. The accurate etiology and …