Abstract Three-dimensional (3D) image reconstruction technologies can reveal previously
hidden microstructures in human tissue. However, the lack of ideal, non-destructive cross …

Ventilation-perfusion matching occurs passively and is also actively regulated through
hypoxic pulmonary vasoconstriction (HPV). The extent of HPV activity in humans, particularly …

We have developed a novel functional proton magnetic resonance imaging (MRI) technique
to measure regional ventilation-perfusion (V̇A/Q̇) ratio in the lung. We conducted a …

Specific ventilation imaging was used to identify regions of the healthy lung (6 supine
subjects, ages 21–41 yr, 3 men) that experienced a fall in specific ventilation following …

Ventilation-perfusion (V̇a/Q̇) mismatch during exercise may result from interstitial
pulmonary edema if increased pulmonary vascular pressure causes fluid efflux into the …

Multi-modality image-guided radiotherapy is the standard of care in contemporary cancer
management; however, it is not common in preclinical settings due to both hardware and …

Measurement of ventilation heterogeneity with the multiple-breath nitrogen washout (MBW)
is usually performed using controlled breathing with a fixed tidal volume and breathing …

Some subjects with asthma have ventilation defects that are resistant to bronchodilator
therapy, and it is thought that these resistant defects may be due to ongoing inflammation or …

Background: To quantify the relationship between regional lung ventilation and coarse
aerosol deposition in the supine healthy human lung, we used oxygen-enhanced magnetic …

High-altitude pulmonary edema (HAPE) is a potentially fatal condition affecting high-altitude
sojourners. The biggest predictor of HAPE development is a history of prior HAPE. Magnetic …