This review summarizes knowledge concerning a ubiquitous plasma transmembraneprotein
family that mediates nucleobase or ascorbate secondary active transport (NAT). We show …

Early genetic and physiological work in bacteria and fungi has suggested the presence of
highly specific nucleobase transport systems. Similar transport systems are now known to …

The study of transporters is highly challenging, as they cannot be isolated or studied in
suspension, requiring a cellular or vesicular system, and, when mediated by more than one …

NCS 1 proteins are H+/Na+ symporters specific for the uptake of purines, pyrimidines and
related metabolites. In this article, we study the origin, diversification and substrate specificity …

We investigated the role of all arrestin‐like proteins of A spergillus nidulans in respect to
growth, morphology, sensitivity to drugs and specifically for the endocytosis and turnover of …

Transporters are transmembrane proteins mediating the selective uptake or efflux of solutes,
metabolites, drugs, or ions across cellular membranes. Despite their immense biological …

Transport assays allow the direct kinetic analysis of a specific transporter by measuring
apparent K m and V max values, and permit the characterization of substrate specificity …

We cloned and characterized an Aspergillus nidulans gene, called fcyB, encoding the
closest homologue to the yeast Fcy2p/Fcy21p permeases. Deletion of fcyB (ΔfcyB) does not …

FurE, a member of the Nucleobase Cation Symporter 1 transporter family in Aspergillus
nidulans, is specific for allantoin, uric acid (UA), uracil, and related analogs. Herein, we …

The function of seven paralogues phylogenetically related to the Saccharomyces cerevisiae
Fur4p together with a number of functionally related transporters present in Aspergillus …