The successful transplantation of stem cells has the potential to transform regenerative
medicine approaches and open promising avenues to repair, replace, and regenerate …

Retinitis pigmentosa (RP) is a heterogeneous group of hereditary diseases characterized by
progressive degeneration of retinal photoreceptors leading to progressive visual decline. It …

Increased oxidative stress in the retina and retinal pigment epithelium is implicated in age-
related macular degeneration (AMD). Antioxidant cerium oxide nanoparticles (CeO2NPs) …

There is a rise in the number of people who have vision loss due to retinal diseases, and
conventional therapies for treating retinal degeneration fail to repair and regenerate the …

Inherited retinal diseases (IRDs) are associated with mutations in over 250 genes and
represent a major cause of irreversible blindness worldwide. While gene augmentation or …

Alteration of the outer retina leads to various diseases such as age-related macular
degeneration or retinitis pigmentosa characterized by decreased visual acuity and ultimately …

Human-induced pluripotent stem cells (hiPSCs) have provided new methods to study
neurodegenerative diseases. In addition to their wide application in neuronal disorders …

Photoreceptors (PRs), as the most abundant and light-sensing cells of the neuroretina, are
responsible for converting light into electrical signals that can be interpreted by the brain. PR …

Replenishing the retina with retinal pigment epithelial (RPE) cells derived from pluripotent
stem cells (PSCs) has great promise for treating retinal degenerative diseases, but it is …

Inherited retinal dystrophies comprise a broad group of genetic eye diseases without
effective treatment. Among them, Stargardt disease is the second most prevalent pathology …