New insights and potential therapeutic targeting of CB2 cannabinoid receptors in CNS disorders

BG Kibret, H Ishiguro, Y Horiuchi, ES Onaivi - International journal of …, 2022 - mdpi.com
The endocannabinoid system (ECS) is ubiquitous in most human tissues, and involved in
the regulation of mental health. Consequently, its dysregulation is associated with …

Potential role of cannabinoid type 2 receptors in neuropsychiatric and neurodegenerative disorders

H Ishiguro, BG Kibret, Y Horiuchi, ES Onaivi - Frontiers in Psychiatry, 2022 - frontiersin.org
The endocannabinoid system (ECS) is composed of the two canonical receptor subtypes;
type-1 cannabinoid (CB1R) and type 2 receptor (CB2R), endocannabinoids (eCBs) and …

Crosstalk between the endocannabinoid and mid-brain dopaminergic systems: Implication in dopamine dysregulation

BG Kibret, A Canseco-Alba, ES Onaivi… - Frontiers in Behavioral …, 2023 - frontiersin.org
Endocannabinoids (eCBs) and the expanded endocannabinoid system (ECS)-
“endocannabinoidome”, consists of the endogenous ligands, eCBs, their canonical and non …

Cannabinoid cb2 receptors in neurodegenerative proteinopathies: New insights and therapeutic potential

B Vuic, T Milos, L Tudor, M Konjevod… - Biomedicines, 2022 - mdpi.com
Some of the most prevalent neurodegenerative disorders, including Alzheimer's and
Parkinson's disease, are proteinopathies characterized by the accumulation of specific …

Cannabinoid receptor 2 selective agonists and Alzheimer's disease: An insight into the therapeutic potentials

SV Magham… - Journal of …, 2021 - Wiley Online Library
Endocannabinoid system has been extensively studied in recent decades, particularly the
cannabinoid receptors CB1 and CB2, due to their important role in neuroinflammation …

[PDF][PDF] Khat-drug interactions: A systematic review

NA Albaser, AWH Mohamad… - … of Pharmacy & …, 2021 - pdfs.semanticscholar.org
Abstract Resumen Context: Consumption of khat leaves has been disseminated worldwide
with the migration of its users from Arabia and Africa. Despite numerous reports regarding …

The impact of catha edulis (vahl) forssk. ex endl. (celestraceae) (khat) on pharmacokinetics of clinically used drugs

E Aklillu, E Engidawork - Expert opinion on drug metabolism & …, 2021 - Taylor & Francis
ABSTRACT Introduction Catha edulis (Vahl) Forssk. ex Endl.(Celestraceae) is used as a
recreational drug on daily basis for its euphoric and psychostimulant effects. It is also …

Role of cannabinoids in inflammation

EJ Downer - Molecules, 2022 - mdpi.com
This Special Issue brings an update on some of the advances in research in the
cannabinoid field, with focus on the impact of cannabinoids on inflammation. The issue …