The emergence of infectious diseases promises to be one of the leading mortality factors in
the healthcare sector. Although several drugs are available on the market, newly found …

Calcium-based (CaXs) biomaterials including calcium phosphates, calcium carbonates,
calcium silicate and calcium fluoride have been widely utilized in the biomedical field owing …

A great deal of research is ongoing in the area of tissue engineering (TE) for bone
regeneration. A possible improvement in restoring damaged tissues involves the loading of …

Microbial resistance to current antibiotics therapies is a major cause of implant failure and
adverse clinical outcomes in orthopaedic surgery. Recent developments in advanced …

Osteomyelitis is a major complication of orthopedic diseases with high recurrence and
morbidity, along with long hospital stays and high medical costs. The conventional treatment …

Chronic osteomyelitis is a challenging disease due to its serious rates of mortality and
morbidity while the currently available treatment strategies are suboptimal. In contrast to the …

The use of nanoparticles has contributed to many advances due to their important properties
such as, size, shape or biocompatibility. The use of nanotechnology in medicine has great …

The spread of antimicrobial resistance in Gram-positive pathogens represents a threat to
human health. To counteract the current lack of novel antibiotics, alternative antibacterial …

Osteomyelitis, or the infection of the bone, presents a major complication in orthopedics and
may lead to prolonged hospital visits, implant failure, and in more extreme cases …

Cockle shell is an external covering of small, salt water edible clams (Anadara granosa) that
dwells in coastal area. This abundant biomaterial is hard, cheap and readily available with …