Biomarkers are an integral part of cancer management due to their use in risk assessment,
screening, differential diagnosis, prognosis, prediction of response to treatment, and …

Thymidine kinase 1 (TK1) is a key enzyme in DNA precursor synthesis. It is upregulated
during the S phase of the cell cycle and its presence in cells is an indicator of active cell …

Nucleotides are synthesized through two distinct pathways: de novo synthesis and
nucleoside salvage. Whereas the de novo pathway synthesizes nucleotides from amino …

Objective: Neutrophil extracellular traps (NETs) can trigger pathological changes in vascular
cells or vessel wall components, which are vascular pathological changes of hypertension …

Inhibition of JAK2/STAT3 Signaling Pathway Suppresses Proliferation of Burkitt’s
Lymphoma Raji Cells via Cell Cycle Progression, Apoptosis, and Oxidative Stress by …

Background Lung, breast, and colorectal malignancies are the leading cause of cancer-
related deaths in the world causing over 2.8 million cancer-related deaths yearly. Despite …

Extracellular vesicles (EVs), whose main subtypes are exosomes, microparticles, and
apoptotic bodies, are secreted by all cells and harbor biomolecules such as DNA, RNA, and …

We chose to evaluate Hypoxanthine Guanine Phosphoribosyltransferase (HPRT) as a
possible biomarker for prostate cancer due to its involvement in nucleotide synthesis and …

Abstract Background Thymidine kinase 1 (TK1) is a pyrimidine salvage pathway enzyme
that is up-regulated in malignant tissues and elevated in the serum of cancer patients. While …

摘要目的: 探讨联合检测血清胸苷激酶1 (TK1) 与乳酸脱氢酶(LDH) 水平在非霍奇金淋巴瘤(NHL
) 患者鉴别诊断及疗效监测中的临床意义. 方法: 收集2016 年1 月至2018 年6 月我院诊治的111 …