Management of non-small-cell lung cancer: recent developments

M Reck, DF Heigener, T Mok, JC Soria, KF Rabe - The Lancet, 2013 - thelancet.com
Non-small-cell lung cancer is one of the leading causes of deaths from cancer worldwide.
Therefore, improvements in diagnostics and treatments are urgently needed. In this review …

Role of postoperative radiotherapy in resected non‐small cell lung cancer: A reassessment based on new data

C Le Péchoux - The oncologist, 2011 - academic.oup.com
Abstract Learning Objectives After completing this course, the reader will be able to: Identify
patients with non‐small cell lung cancer who may benefit from postoperative radiotherapy …

Treatment of stage III non-small cell lung cancer: Diagnosis and management of lung cancer: American College of Chest Physicians evidence-based clinical practice …

N Ramnath, TJ Dilling, LJ Harris, AW Kim, GC Michaud… - Chest, 2013 - Elsevier
Objectives Stage III non-small cell lung cancer (NSCLC) describes a heterogeneous
population with disease presentation ranging from apparently resectable tumors with occult …

A phase 3 study of induction treatment with concurrent chemoradiotherapy versus chemotherapy before surgery in patients with pathologically confirmed N2 stage IIIA …

N Katakami, H Tada, T Mitsudomi, S Kudoh, H Senba… - Cancer, 2012 - Wiley Online Library
BACKGROUND: This study sought to ascertain whether induction‐concurrent radiotherapy
added to chemotherapy could improve the survival of patients undergoing surgery for stage …

[HTML][HTML] Definitive radiochemotherapy versus surgery within multimodality treatment in stage III non-small cell lung cancer (NSCLC)-a cumulative meta-analysis of the …

C Pöttgen, W Eberhardt, G Stamatis, M Stuschke - Oncotarget, 2017 - ncbi.nlm.nih.gov
Randomized trials were analyzed comparing surgery with definitive radiotherapy as local
curative treatment options within the framework of different multimodality treatments for …

[HTML][HTML] Pathologic complete response to preoperative chemotherapy predicts cure in early-stage non–small-cell lung cancer: combined analysis of two IFCT …

G Mouillet, E Monnet, B Milleron, M Puyraveau… - Journal of Thoracic …, 2012 - Elsevier
Introduction: Our study aimed to evaluate whether pathologic complete response (pCR) in
early-stage non–small-cell lung cancer (NSCLC) after neoadjuvant chemotherapy resulted …

[HTML][HTML] Identification of residual metabolic-active areas within NSCLC tumours using a pre-radiotherapy FDG-PET-CT scan: a prospective validation

HJWL Aerts, J Bussink, WJG Oyen, W van Elmpt… - Lung cancer, 2012 - Elsevier
It was recently described that high FDG-uptake areas pre-radiotherapy largely correspond
with residual metabolic-active areas post-radiotherapy. Here, an independent prospective …

Radiotherapy versus surgery within multimodality protocols for esophageal cancer–a meta-analysis of the randomized trials

C Pöttgen, M Stuschke - Cancer treatment reviews, 2012 - Elsevier
During recent years, the curative potential of radiotherapy versus surgery for esophageal
cancer was investigated in randomized trials. A PubMED®, Medline®, and Web of Science® …

[HTML][HTML] Improved survival associated with neoadjuvant chemoradiation in patients with clinical stage IIIA (N2) non–small-cell lung cancer

M Koshy, SA Fedewa, R Malik, MK Ferguson… - Journal of Thoracic …, 2013 - Elsevier
Introduction Optimal management of clinical stage IIIA-N2 non–small-cell lung cancer
(NSCLC) is controversial. This study examines whether neoadjuvant chemoradiation plus …

Salvage surgery after definitive chemoradiotherapy for non–small cell lung cancer

M Casiraghi, P Maisonneuve, G Piperno… - Seminars in Thoracic …, 2017 - Elsevier
Following definitive chemoradiation therapy, 24%-35% of patients with locally advanced non–
small cell lung cancer have recurrence. We aimed to evaluate the feasibility of salvage …