Introduction: The carbonic anhydrases (CAs, EC 4.2. 1.1), a group of ubiquitously expressed
metalloenzymes, are involved in numerous physiological and pathological processes, as …

The possibility to develop new antibacterial agents raised much interest recently. The main
classes of antibiotics clinically used nowadays act towards the inhibition of four classical …

Background In recent decades, the world has witnessed unprecedented progress in child
survival. However, our knowledge of what is killing nearly 6 million children annually in low …

Abstract The Manhiça Health Research Centre, established in 1996 in a rural area of
southern Mozambique, currently follows around 92 000 individuals living in approximately …

Background. There is some consensus that malaria in pregnancy may negatively affect
infant's mortality and malaria morbidity, but there is less evidence concerning the factors …

Background Diarrheal disease remains a leading cause of illness and death, particularly in
low-income countries. Its burden, microbiological causes and risk factors were examined in …

We report and explore changes in child mortality in a rural area of Kenya during 2003–2009,
when major public health interventions were scaled-up. Mortality ratios and rates were …

BACKGROUND: Although the burden of postdischarge mortality (PDM) in low-income
settings appears to be significant, no clear recommendations have been proposed in …

Despite the protection provided by several factors, including maternal antibodies, the burden
of malaria in young infants may be higher than previously thought. Infants with congenital or …

Background: Morbidity and mortality from childhood illnesses has remained a major point of
interest globally. Malaria, respiratory tract infection and diarrheal diseases are the leading …