Mesenchymal stem cell secretome for dermatology application: a review

RH Damayanti, T Rusdiana… - Clinical, cosmetic and …, 2021 - Taylor & Francis
Secretome, also known as conditioned medium, is a secreted molecule from mesenchymal
stem cells (MSCs) that has a variety of biological activities that can be used in various …

Mesenchymal stem cells-derived secretome and extracellular vesicles: perspective and challenges in cancer therapy and clinical applications

J Gemayel, D Chaker, G El Hachem, M Mhanna… - Clinical and …, 2023 - Springer
Stem cell-based therapies have been foreshowed as a promising therapeutic approach for
the treatment of several diseases. However, in the cancer context, results obtained from …

Progress in the development of stem cell-derived cell-free therapies for skin aging

Y Chou, NM Alfarafisa, M Ikezawa… - Clinical, Cosmetic and …, 2023 - Taylor & Francis
Introduction The skin is a vital organ as the body's largest barrier, but its function declines
with aging. Therefore, research into effective regeneration treatments must continue to …

[HTML][HTML] In vitro effects of conditioned medium from bioreactor cultured human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) on skin-derived cell lines

YM Park, MJ Lee, SH Jeon, D Hrůzová - Regenerative Therapy, 2021 - Elsevier
Introduction When stem cells are grafted into tissues, they differentiate and form specialized
cells. However, the proficiency of stem cells to endure and assimilate the host cell is …

Effect of stem cell secretome in skin rejuvenation: a narrative review

R Hani, L Khayat, AA Rahman, N Alaaeddine - Molecular Biology Reports, 2023 - Springer
Purpose Cutaneous aging is an inevitable biological process that develops over time due to
cumulative cellular and molecular changes caused by exposure to intrinsic (chronological …

[HTML][HTML] IL-11 and soluble VCAM-1 are important components of Hypoxia Conditioned Media and crucial for Mesenchymal Stromal Cells attraction

A Gabrielyan, M Quade, M Gelinsky, A Rösen-Wolff - Stem cell research, 2020 - Elsevier
Introduction Bone marrow stromal cells (BMSC) are highly attractive for tissue engineering
due to their ability to differentiate into different cell types, to expand extensively in vitro and to …

Effect of Multiple-Cycle Collections of Conditioned Media from Different Cell Sources towards Fibroblasts in In Vitro Wound Healing Model

NIM Fadilah, MB Fauzi, M Maarof - Pharmaceutics, 2024 - mdpi.com
Conditioned media refers to a collection of the used cell culture media. The goal of this study
was to evaluate the possible impacts of different conditioned media collected across a …

[HTML][HTML] Potential antiaging activity of secretome gel of human Wharton's jelly mesenchymal stem cells (hWJ-MSCs) in UV-induced mice models

W Widowati, A Faried, A Adam, D Rahmat… - Iranian journal of …, 2024 - ncbi.nlm.nih.gov
Objective (s): Skin aging is a degenerative process that can be induced by UV irradiation.
UV radiation can produce reactive oxidate stress which causes premature aging. This study …

Mesenchymal Stem cell-Conditioned Medium (secretome) in skin aging A systematic review

WE Putri, A Endaryanto, FA Rantam… - International …, 2021 - repository.unusa.ac.id
Background: The skin aging is the most important factor that constitutes the general" well-
being" and perception of" health" in humans. The mesenchymal stem cells (MSCs) have a …

Effect of secretome of adipose stem cell (ASC) in photoaging skin

WE Putri, A Endaryanto, D Tinduh… - Bali Medical …, 2022 - repository.unusa.ac.id
Introduction: UV light is the principal cause of photoaging, a kind of aging. The problem
arises because it is less enjoyable. Utilizing the secretome of adipose stem cells (ASC) …