Rheumatoid arthritis (RA) is a chronic immune-mediated disease that primarily affects the
synovium of diarthrodial joints. During the course of RA, the synovium transforms into a …

Over the last decade, many epigenetic mechanisms that contribute in the pathogenesis of
autoimmune disorders have been revealed. MicroRNAs (miRNAs) are small, non-coding …

MicroRNAs (miRNAs) are short non-coding RNAs that act as important regulators of gene
expression as part of the epigenetic machinery. In addition to posttranscriptional gene …

The tumor suppressor p53 is one of the most frequently mutated genes in human cancers.
MicroRNAs (miRNAs) are small non-protein coding RNAs that regulate gene expression on …

Rheumatoid arthritis (RA) is a polygenic disease characterized by autoimmunity and
systemic inflammation with progressive impairment of joints that results in lifelong disability …

Rheumatoid arthritis (RA) is a systemic autoimmune disease that affects about 1% of the
world's population. The etiology of RA remains unknown. It is considered to occur in the …

MicroRNAs (miRNAs) are small, single-stranded, endogenous non-coding RNAs that
repress the expression of target genes via post-transcriptional mechanisms. Due to their …

Swelling and the progressive destruction of articular cartilage are major characteristics of
rheumatoid arthritis (RA), a systemic autoimmune disease that directly affects the synovial …

Within the past years, more and more attention has been devoted to the epigenetic
dysregulation that provides an additional window for understanding the possible …

In the past decade, we have witnessed considerable developments in understanding the
roles and functions of miRNAs. In parallel, the identification of alterations in miRNA …