Hip and knee osteoarthritis (OA) are leading causes of global disability. Most research to
date has focused on the knee, with results often extrapolated to the hip, and this extends to …

Objective In this review, we have highlighted the advances over the past year in genetics,
genomics and epigenetics in the field of osteoarthritis (OA). Methods A literature search of …

Cartilage homeostasis is essential for chondrocytes to maintain proper phenotype and
metabolism. Because adult articular cartilage is avascular, chondrocytes must survive in low …

Osteoarthritis (OA) occurs mostly in the knees, hips, finger interphalangeal joints, and spinal
facet joints, and is characterized by cartilage degeneration. The existing bulk RNA …

Abstract Objective Long noncoding RNAs (lncRNAs) regulate the occurrence and
development of osteoarthritis (OA), whereas the biological roles and mechanisms of the …

During the last decade, osteoarthritis (OA) has become one of the most prevalent
musculoskeletal diseases worldwide. OA is characterized by progressive loss of articular …

Osteoarthritis is a leading cause of disability in the world. The scientific literature highlights
the critical importance of epigenetic regulatory effects, intertwined with biomechanical and …

Multitissue interactions (cartilage–subchondral bone; cartilage–synovium) are prevalent in
the pathophysiology of osteoarthritis, which is characterized by substantial matrix …

Osteoarthritis is a prevalent joint disease and a major cause of disability worldwide with no
curative therapy. Development of disease-modifying therapies requires a better …

Osteoarthritis (OA) is a prevalent joint disease, which is associated with progressive articular
cartilage loss, synovial inflammation, subchondral sclerosis and meniscus injury. The …