Functional constipation is common in children and adults worldwide. Functional constipation
shows similarities in children and adults, but important differences also exist regarding …

Paediatric functional abdominal pain disorders, currently referred to as disorders of gut–
brain interaction, comprise irritable bowel syndrome, functional dyspepsia, abdominal …

Diagnosis or exclusion of Hirschsprung disease (HSCR) is a frequent exercise in any
pediatric hospital. Although HSCR may present at different ages and with varied clinical …

This review intends to update what is known about and what is still a challenge in functional
constipation (FC) in children regarding epidemiology, pathophysiology, diagnosis, and …

Children with Hirschsprung disease have postoperative long-term sequelae in defecation
that contribute to morbidity and mortality and significantly impact their quality of life. Pediatric …

Background Upper gastrointestinal symptoms in children are common and motility disorders
are considered in the differential diagnosis. High resolution esophageal manometry (HRM) …

We report the first study assessing human colon manometric features and their correlations
with changes in autonomic functioning in patients with refractory chronic constipation prior to …

Defecation is a complex physiological process, which relies on intricate mechanisms
involving the autonomic and somatic nervous system, the pelvic floor muscles, and the anal …

Background High‐resolution colonic manometry gives an unprecedented window into motor
patterns of the human colon. Our objective was to characterize motor activities throughout …

Although most children with Hirschsprung disease ultimately achieve functional and
comfortable stooling, some will experience a variety of problems after pull-through surgery …