Collective cell migration critically depends on cell–cell interactions coupled to a dynamic
actin cytoskeleton. Important cell–cell adhesion receptor systems implicated in controlling …

Highlights•Regeneration of the PNS is a complex, highly coordinated, multicellular process.•
Macrophages have multiple roles to condition the environment for axonal …

INTRODUCTION Cell differentiation is classically described as a unidirectional process that
progresses through a series of lineage restriction events, with cellular potential being …

Cells have traditionally been viewed either as independently moving entities or as
somewhat static parts of tissues. However, it is now clear that in many cases, multiple cells …

Swarming or collective motion of living entities is one of the most common and spectacular
manifestations of living systems that have been extensively studied in recent years. A …

Our understanding of the neural crest, a key vertebrate innovation, is built upon studies of
multiple model organisms. Early research on neural crest cells (NCCs) was dominated by …

Contact inhibition of locomotion (CIL) is a complex process, whereby cells undergoing a
collision with another cell cease their migration towards the colliding cell. CIL has been …

Neuroblastoma (NB) is a childhood cancer arising from sympatho-adrenal neural crest cells.
Disseminated forms have high frequency of multiple tumoral foci whose etiology remains …

Perturbations in cardiac development result in congenital heart disease, the leading cause
of birth defect–related infant morbidity and mortality. Advances in cardiac developmental …

Developmental potential is progressively restricted after germ layer specification during
gastrulation. However, cranial neural crest cells challenge this paradigm, as they develop …