Hyper-induction of pro-inflammatory cytokines, also known as a cytokine storm or cytokine
release syndrome (CRS), is one of the key aspects of the currently ongoing SARS-CoV-2 …

In the face of the Covid-19 pandemic, an intensive number of studies have been performed
to understand in a deeper way the mechanisms behind better or worse clinical outcomes …

Immune and inflammatory responses to severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) contribute to disease severity of coronavirus disease 2019 (COVID-19) …

COVID-19 exhibits extensive patient-to-patient heterogeneity. To link immune response
variation to disease severity and outcome over time, we longitudinally assessed circulating …

Epidemiological and clinical reports indicate that SARS-CoV-2 virulence hinges upon the
triggering of an aberrant host immune response, more so than on direct virus-induced …

The outbreak of coronavirus disease 2019 (COVID-19) is caused by the infection of severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which leads to the disruption of …

Background Knowledge of the pathophysiology of COVID-19 is almost exclusively derived
from studies that examined the immune response in blood. We here aimed to analyse the …

Due to the dysregulated and overexuberant innate immune responses, a sizeable number of
patients had succumbed worldwide, due to coronavirus disease 2019 (COVID-19) mediated …

The pathological processes by severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) infection that make the virus a major threat to global health are insufficiently …

Cytokines, chemokines and growth factors present different expression profiles related to the
prognosis of COVID-19. We analyzed clinical parameters and assessed the expression of …