Isolated brain tissue, especially brain slices, are valuable experimental tools for studying
neuronal function at the network, cellular, synaptic, and single channel levels …

Our insights into the basic characteristics of neuronal function were significantly advanced
by combining the in vitro slice technique with the visualization of neurons and their …

The pineal hormone melatonin elicits two effects on the suprachiasmatic nuclei (SCN): acute
neuronal inhibition and phase-shifting. Melatonin evokes its biological effects through G …

A direct comparison was made of the effects of serotonin 5‐HT1A and 5‐HT1B selective
compounds on the spontaneous firing rate of dorsal raphe serotoninergic neurons in chloral …

Extracellular and intracellular recordings were made from dorsal raphe (DR) neurons in
frontal rat brain slices maintained in vitro. A population of neurons was found which …

Long-term potentiation (LTP) is a use-dependent form of synaptic plasticity that is of great
interest as a potential cellular substrate underlying memory. It is important to determine the …

The synchronization of neuronal firing, seen at its most dramatic in the epilepsies, has
generally been attributed to synaptic interactions1–5. We have now discovered a rhythmic …

In general, it has been difficult to preserve electrophysiologically viable motoneurons in
brain slices from adult mammals. The present study describes a new method for obtaining …

It has been proposed that three major receptor subtypes subserve the putative transmitter
role of glutamate and aspartate in the mammalian central nervous system. One subtype is …

Activation of γ-aminobutyric acid (GABA A) receptors have been associated with the onset of
epileptiform events. To investigate if a causal relationship exists between GABA A receptor …