Diabetic kidney disease has a high global disease burden and substantially increases the
risk of kidney failure and cardiovascular events. Despite treatment, there is substantial …

Globally, the incidence and prevalence of diabetes mellitus has risen dramatically, owing
mainly to the increase in type 2 diabetes mellitus (T2DM). In 2021, 537 million people …

An essential step in renal function entails the formation of an ultrafiltrate that is delivered to
the renal tubules for subsequent processing. This process, known as glomerular filtration, is …

Diabetic kidney disease (DKD) is the leading cause of chronic kidney disease, including end-
stage kidney disease, and increases the risk of cardiovascular mortality. Although the …

Persons with diabetes and chronic kidney disease (CKD) have a high residual risk of
developing cardiovascular (CV) complications despite treatment with renin-angiotensin …

The spectrum of cardiorenal and metabolic diseases comprises many disorders, including
obesity, type 2 diabetes (T2D), chronic kidney disease (CKD), atherosclerotic cardiovascular …

Aims Our previous studies showed that the nonsteroidal anti-inflammatory drug-activated
gene-1, or growth differentiation factor-15 (NAG-1/GDF15) inhibits obesity and diabetes in …

The purpose of this study is to assess the safety and efficacy of finerenone therapy in type 2
diabetes mellitus (T2DM) patients with cardiovascular and chronic renal diseases. This meta …

Diabetes is the most frequent cause of kidney disease that progresses to end-stage renal
disease worldwide, and diabetic kidney disease is significantly related to unfavorable …

Background In patients with type 2 diabetes (T2D), risks of cardiovascular mortality and
heart failure (HF) increase with decreasing kidney function (estimated glomerular filtration …