Biomolecular condensates are membraneless intracellular assemblies that often form via
liquid− liquid phase separation and have the ability to concentrate biopolymers. Research …

Biomolecular condensates, membrane-less entities arising from liquid–liquid phase
separation, hold dichotomous roles in health and disease. Alongside their physiological …

INTRODUCTION Stress granules are dynamic structures composed of RNA and protein that
arise in the cytoplasm in response to a variety of stressors. These structures form via liquid …

Autophagy contributes to the selective degradation of liquid droplets, including the P-
Granule, Ape1-complex and p62/SQSTM1-body, although the molecular mechanisms and …

The proteasome is a major proteolytic machine that regulates cellular proteostasis through
selective degradation of ubiquitylated proteins,. A number of ubiquitin-related molecules …

Stress granules (SGs) are cytosolic biomolecular condensates that form in response to
cellular stress. Weak, multivalent interactions between their protein and RNA constituents …

INTRODUCTION In response to many types of stress, eukaryotic cells initiate an adaptive
and reversible response that includes down-regulation of key cellular activities along with …

Stress granules (SGs) are cytoplasmic assemblies of proteins and non-translating mRNAs.
Whereas much has been learned about SG formation, a major gap remains in …

Stress granules (SGs) form during cellular stress and are implicated in neurodegenerative
diseases such as amyotrophic lateral sclerosis and frontotemporal dementia (ALS/FTD). To …

Eukaryotic stress granules (SGs) are highly dynamic assemblies of untranslated mRNAs
and proteins that form through liquid-liquid phase separation (LLPS) under cellular stress …