Recent years have witnessed increasingly rapid advances in nanocarrier-based
biomedicine aimed at improving treatment paradigms for cancer. Nanogels serve as …

Nanogels, also termed hydrogel nanoparticles, have the properties and functions of both
nanomaterials and hydrogels. Till date, a considerable number of nanogels have been …

Personalized tumor vaccines have become a promising modality for cancer immunotherapy.
However, in situ personalized tumor vaccines generated from immunogenic cancer cell …

Immunotherapy has emerged as an eminent and effective modality in the treatment of
cancer. However, current cancer immunotherapies lack spatial and temporal control …

Although cancer immunotherapy based on immune checkpoint blockade has shown
promising clinical responses, the limited host response rate and systemic side effects still …

In therapeutic cancer vaccines, vaccine antigens must be efficiently delivered to the antigen-
presenting cells (dendritic cells and macrophages) located in the lymphoid organs (lymph …

Mono‐chemotherapy has significant side effects and unsatisfactory efficacy, limiting its
clinical application. Therefore, a combination of multiple treatments is becoming more …

Cancer is complicated to treat because of its high propensity for recurrence and metastasis,
and various side effects of conventional cancer treatments. With the development of …

The design of functional polymers coupled with stimuli-triggered drug release mechanisms
is a promising achievement to overcome various biological barriers. pH trigger methods …

Immune-suppressive (M2-type) macrophages can contribute to the progression of cancer
and fibrosis. In chronic liver diseases, M2-type macrophages promote the replacement of …