Researchers have recently focused on the advancement of new materials from
biorenewable and sustainable sources because of great concerns about the environment …

Nanotopography presents an effective physical approach for biomaterial cell manipulation
mediated through material-extracellular matrix interactions. The extracellular matrix that …

Abstract The role of Bone Tissue Engineering in the field of Regenerative Medicine has
been the topic of substantial research over the past two decades. Technological advances …

During recent decades vast and continuously increasing numbers of biomedical implants
have been introduced for continuous use in the human body. Since the early cemented hip …

Joint replacement is a major orthopaedic procedure used to treat joint osteoarthritis. Aseptic
loosening and infection are the two most significant causes of prosthetic implant failure. The …

Nanocomposites have emerged in the last two decades as an efficient strategy to upgrade
the structural and functional properties of synthetic polymers. Aliphatic polyesters as …

Hydroxyapatite has become an important coating material for bioimplants, following the
introduction of synthetic HAp in the 1950s. The HAp coatings require controlled surface …

The stiffness and nanotopographical characteristics of the extracellular matrix (ECM)
influence numerous developmental, physiological, and pathological processes in vivo …

The current development of nanobiotechnologies requires a better understanding of cell–
surface interactions on the nanometre scale. Recently, advances in nanoscale patterning …

Cells are inherently sensitive to local mesoscale, microscale, and nanoscale patterns of
chemistry and topography. We review current approaches to control cell behavior through …