Pancreatic cancer epidemiology: understanding the role of lifestyle and inherited risk factors
AP Klein - Nature reviews Gastroenterology & hepatology, 2021 - nature.com
Pancreatic cancer is a leading cause of cancer death worldwide and its global burden has
more than doubled over the past 25 years. The highest incidence regions for pancreatic …
more than doubled over the past 25 years. The highest incidence regions for pancreatic …
Pancreatic cancer
Pancreatic cancer is a major cause of cancer-associated mortality, with a dismal overall
prognosis that has remained virtually unchanged for many decades. Currently, prevention or …
prognosis that has remained virtually unchanged for many decades. Currently, prevention or …
Ferroptosis of tumour neutrophils causes immune suppression in cancer
R Kim, A Hashimoto, N Markosyan, VA Tyurin… - Nature, 2022 - nature.com
Ferroptosis is a non-apoptotic form of regulated cell death that is triggered by the
discoordination of regulatory redox mechanisms culminating in massive peroxidation of …
discoordination of regulatory redox mechanisms culminating in massive peroxidation of …
Integrated genomic characterization of pancreatic ductal adenocarcinoma
We performed integrated genomic, transcriptomic, and proteomic profiling of 150 pancreatic
ductal adenocarcinoma (PDAC) specimens, including samples with characteristic low …
ductal adenocarcinoma (PDAC) specimens, including samples with characteristic low …
Patterns, timing, and predictors of recurrence following pancreatectomy for pancreatic ductal adenocarcinoma
Objective: To describe accurately the pattern, timing, and predictors of disease recurrence
after a potentially curative resection for pancreatic ductal adenocarcinoma (PDAC) …
after a potentially curative resection for pancreatic ductal adenocarcinoma (PDAC) …
PD-1/PD-L1 blockade together with vaccine therapy facilitates effector T-cell infiltration into pancreatic tumors
Pancreatic ductal adenocarcinoma (PDA) has a poor prognosis due to late detection and
resistance to conventional therapies. Published studies show that the PDA tumor …
resistance to conventional therapies. Published studies show that the PDA tumor …
Recent trends in the incidence and survival of stage 1A pancreatic cancer: a surveillance, epidemiology, and end results analysis
Background Rapid access to pancreatic imaging and regular pancreatic surveillance may
help identify stage I pancreatic cancer. We investigated recent trends in the stage of newly …
help identify stage I pancreatic cancer. We investigated recent trends in the stage of newly …
Neoadjuvant therapy for resectable and borderline resectable pancreatic cancer: a meta-analysis of randomized controlled trials
The efficacy of neoadjuvant therapy (NT) versus surgery first (SF) for pancreatic ductal
adenocarcinoma (PDAC) remains controversial. A random-effects meta-analysis of only …
adenocarcinoma (PDAC) remains controversial. A random-effects meta-analysis of only …
Survival outcomes associated with clinical and pathological response following neoadjuvant FOLFIRINOX or gemcitabine/nab-paclitaxel chemotherapy in resected …
FI Macedo, E Ryon, SK Maithel, RM Lee… - Annals of …, 2019 - journals.lww.com
Objective: To compare the survival outcomes associated with clinical and pathological
response in pancreatic ductal adenocarcinoma (PDAC) patients receiving neoadjuvant …
response in pancreatic ductal adenocarcinoma (PDAC) patients receiving neoadjuvant …
Is a pathological complete response following neoadjuvant chemoradiation associated with prolonged survival in patients with pancreatic cancer?
Objectives: To describe the survival outcome of patients with borderline resectable or locally
advanced pancreatic ductal adenocarcinoma (BR/LA-PDAC) who have a pathologic …
advanced pancreatic ductal adenocarcinoma (BR/LA-PDAC) who have a pathologic …