Thiazolidinediones and PPAR orchestra as antidiabetic agents: From past to present

S Yasmin, V Jayaprakash - European journal of medicinal chemistry, 2017 - Elsevier
Thiazolidinediones a class of drug, that provided a major breakthrough in the management
of type 2 diabetes since 1990. Following the discovery of PPARs, TZDs were the first class to …

An insulin sensitizer improves the free radical defense system potential and insulin sensitivity in high fructose-fed rats.

P Faure, E Rossini, N Wiernsperger, MJ Richard… - Diabetes, 1999 - Am Diabetes Assoc
Recently there has been growing interest in the effects of antioxidants on insulin activity. In
the present study, we investigated the effect of metformin on free radical activity and insulin …

[HTML][HTML] Antioxidant effect of pomegranate against streptozotocin-nicotinamide generated oxidative stress induced diabetic rats

A Aboonabi, A Rahmat, F Othman - Toxicology Reports, 2014 - Elsevier
Oxidative stress attributes a crucial role in chronic complication of diabetes. The aim of this
study was to determine the most effective part of pomegranate on oxidative stress markers …

Evaluation of the Hypoglycemic, Hypolipidemic and Antioxidant Effects of Methanolic Extract of" Ata-Ofa" Polyherbal Tea (APolyherbal) in Alloxan-Induced Diabetic …

SE Atawodi - Drug Invention Today, 2011 - search.ebscohost.com
Abstract Methanolic extract of" Ata-Ofa Polyherbal tea"(A-Polyherbal) was evaluated for
hypoglycemic, hypolipidemic and antioxidant effects in alloxan-induced diabetic rats …

Novel benzylidene thiazolidinedione derivatives as partial PPARγ agonists and their antidiabetic effects on type 2 diabetes

S Yasmin, F Capone, A Laghezza, FD Piaz… - Scientific Reports, 2017 - nature.com
Peroxisome proliferator-activated receptor γ (PPARγ) has received significant attention as a
key regulator of glucose and lipid homeostasis. In this study, we synthesized and tested a …

[PDF][PDF] Efficacy of aqueous extract of seed of Holarrhena antidysenterica for the management of diabetes in experimental model rat: A correlative study with …

KM Ali, K Chatterjee, BTK De D… - Int J Appl Res Nat Prod, 2009 - researchgate.net
The present study reports the effects of aqueous extract of seed of Holarrhena
antidysenterica for the management of streptozotocin (STZ) induced diabetes in rat. For the …

Protective role of glibenclamide against nicotinamidestreptozotocin induced nuclear damage in diabetic Wistar rats

SI Rabbani, K Devi, S Khanam - Journal of Pharmacology …, 2010 - journals.sagepub.com
Objective: To evaluate the protective effect of glibenclamide against the experimental
diabetes-induced nuclear damage in Wistar rats. Materials and Methods: The anti …

A series of ferulic acid amides reveals unexpected peroxiredoxin 1 inhibitory activity with in vivo antidiabetic and hypolipidemic effects

S Yasmin, C Cerchia, VN Badavath… - …, 2021 - Wiley Online Library
Insulin resistance is a major pathophysiological feature in the development of type 2
diabetes (T2DM). Ferulic acid is known for attenuating the insulin resistance and reducing …

Antiperoxidative and antioxidant effects of Casearia esculenta root extract in streptozotocin-induced diabetic rats.

A Prakasam, S Sethupathy… - The Yale journal of …, 2005 - ncbi.nlm.nih.gov
Oxidative stress is currently suggested to play as a pathogenesis in the development of
diabetes mellitus. The present study was designed to evaluate the effect of Casearia …

Anti-diabetic activity and safety assessment of Ayurvedic medicine, Jasada bhasma (zinc ash) in rats

RD Umrani, DS Agrawal, KM Paknikar - 2013 - nopr.niscpr.res.in
Jasada bhasma (zinc ash) is an extensively used Ayurvedic medicine for treating diabetes
mellitus. The present communication presents yet unavailable comprehensive scientific data …