Molecular mechanism of interaction between SARS-CoV-2 and host cells and interventional therapy
Q Zhang, R Xiang, S Huo, Y Zhou, S Jiang… - Signal transduction and …, 2021 - nature.com
The pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) infection has resulted in an unprecedented setback …
syndrome coronavirus 2 (SARS-CoV-2) infection has resulted in an unprecedented setback …
A systematic review of SARS-CoV-2 vaccine candidates
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an emerging virus that is
highly pathogenic and has caused the recent worldwide pandemic officially named …
highly pathogenic and has caused the recent worldwide pandemic officially named …
[HTML][HTML] COVID-19-neutralizing antibodies predict disease severity and survival
WF Garcia-Beltran, EC Lam, MG Astudillo, D Yang… - Cell, 2021 - cell.com
Summary Coronavirus disease 2019 (COVID-19) exhibits variable symptom severity ranging
from asymptomatic to life-threatening, yet the relationship between severity and the humoral …
from asymptomatic to life-threatening, yet the relationship between severity and the humoral …
COVID-19 vaccines: The status and perspectives in delivery points of view
Due to the high prevalence and long incubation periods often without symptoms, the severe
acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has infected millions of individuals …
acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has infected millions of individuals …
COVID-19 vaccine development and a potential nanomaterial path forward
MD Shin, S Shukla, YH Chung, V Beiss… - Nature …, 2020 - nature.com
The COVID-19 pandemic has infected millions of people with no clear signs of abatement
owing to the high prevalence, long incubation period and lack of established treatments or …
owing to the high prevalence, long incubation period and lack of established treatments or …
[HTML][HTML] Deep mutational scanning of SARS-CoV-2 receptor binding domain reveals constraints on folding and ACE2 binding
The receptor binding domain (RBD) of the SARS-CoV-2 spike glycoprotein mediates viral
attachment to ACE2 receptor and is a major determinant of host range and a dominant target …
attachment to ACE2 receptor and is a major determinant of host range and a dominant target …
Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model
Countermeasures to prevent and treat coronavirus disease 2019 (COVID-19) are a global
health priority. We enrolled a cohort of severe acute respiratory syndrome coronavirus 2 …
health priority. We enrolled a cohort of severe acute respiratory syndrome coronavirus 2 …
The SARS-CoV-2 spike glycoprotein biosynthesis, structure, function, and antigenicity: implications for the design of spike-based vaccine immunogens
L Duan, Q Zheng, H Zhang, Y Niu, Y Lou… - Frontiers in …, 2020 - frontiersin.org
The ongoing pandemic of coronavirus disease 2019 (COVID-19), caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), poses a grave threat to global public …
respiratory syndrome coronavirus 2 (SARS-CoV-2), poses a grave threat to global public …
[HTML][HTML] Structures of human antibodies bound to SARS-CoV-2 spike reveal common epitopes and recurrent features of antibodies
CO Barnes, AP West, KE Huey-Tubman… - Cell, 2020 - cell.com
Neutralizing antibody responses to coronaviruses mainly target the receptor-binding domain
(RBD) of the trimeric spike. Here, we characterized polyclonal immunoglobulin Gs (IgGs) …
(RBD) of the trimeric spike. Here, we characterized polyclonal immunoglobulin Gs (IgGs) …
Protocol and reagents for pseudotyping lentiviral particles with SARS-CoV-2 spike protein for neutralization assays
SARS-CoV-2 enters cells using its Spike protein, which is also the main target of neutralizing
antibodies. Therefore, assays to measure how antibodies and sera affect Spike-mediated …
antibodies. Therefore, assays to measure how antibodies and sera affect Spike-mediated …