Interaction between N6-methyladenosine (m6A) modification and noncoding RNAs in cancer

Y Chen, Y Lin, Y Shu, J He, W Gao - Molecular cancer, 2020 - Springer
As a critical internal RNA modification in higher eukaryotes, N 6-methyladenosine (m 6 A)
has become the hotspot of epigenetics research in recent years. Extensive studies on …

mRNA modifications in cardiovascular biology and disease: with a focus on m6A modification

R Kumari, P Ranjan, ZG Suleiman… - Cardiovascular …, 2022 - academic.oup.com
Among several known RNA modifications, N6‐methyladenosine (m6A) is the most studied
RNA epitranscriptomic modification and controls multiple cellular functions during …

Aberrations of m6A regulators are associated with tumorigenesis and metastasis in head and neck squamous cell carcinoma

P Arumugam, R George, VP Jayaseelan - Archives of oral biology, 2021 - Elsevier
Abstract Objective N6-Methyladenosine (m6A) is the most common RNA modification in
eukaryotic mRNAs and growing evidence suggests that m6A modification and its regulators …

[HTML][HTML] The m6A readers YTHDF1 and YTHDF3 aberrations associated with metastasis and predict poor prognosis in breast cancer patients

R Anita, A Paramasivam, JV Priyadharsini… - American journal of …, 2020 - ncbi.nlm.nih.gov
Abstract N6-Methyladenosine (m6A) is the most common RNA modification in eukaryotic
mRNAs and growing evidence suggests the crucial roles of m6A and its regulators in human …

Research progress on circular RNA vaccines

Y Bai, D Liu, Q He, J Liu, Q Mao, Z Liang - Frontiers in immunology, 2023 - frontiersin.org
Owing to the success of linear mRNA coronavirus disease 2019 (COVID-19) vaccines,
biopharmaceutical companies and research teams worldwide have attempted to develop …

The m6A reader IMP2 directs autoimmune inflammation through an IL-17– and TNFα-dependent C/EBP transcription factor axis

R Bechara, N Amatya, RD Bailey, Y Li, FEY Aggor… - Science …, 2021 - science.org
Excessive cytokine activity underlies many autoimmune conditions, particularly through the
interleukin-17 (IL-17) and tumor necrosis factor–α (TNFα) signaling axis. Both cytokines …

Mechanisms of circular RNA degradation

L Ren, Q Jiang, L Mo, L Tan, Q Dong, L Meng… - Communications …, 2022 - nature.com
Abstract Circular RNAs (CircRNAs) are a class of noncoding RNAs formed by backsplicing
during cotranscriptional and posttranscriptional processes, and they widely exist in various …

The role of m6A epigenetic modifications in tumor coding and non-coding RNA processing

T Wen, T Li, Y Xu, Y Zhang, H Pan, Y Wang - Cell Communication and …, 2023 - Springer
Background Epigenetic modifications of RNA significantly contribute to the regulatory
processes in tumors and have, thus, received considerable attention. The m6A modification …

The functions and clinical significance of circRNAs in hematological malignancies

X Zhou, L Zhan, K Huang, X Wang - Journal of hematology & oncology, 2020 - Springer
With covalently closed circular structures, circular RNAs (circRNAs) were once
misinterpreted as by-products of mRNA splicing. Being abundant, stable, highly conserved …

[HTML][HTML] Crosstalk between N6-methyladenosine (m6A) modification and noncoding RNA in tumor microenvironment

D Wang, Y Han, L Peng, T Huang, X He… - … Journal of Biological …, 2023 - ncbi.nlm.nih.gov
Abstract N6-methyladenosine (m6A) is the most abundant RNA modification in eukaryotes,
and it participates in the regulation of pathophysiological processes in various diseases …