[HTML][HTML] Spatial dysregulation of T follicular helper cells impairs vaccine responses in aging
A Silva-Cayetano, S Fra-Bido, PA Robert… - Nature …, 2023 - nature.com
The magnitude and quality of the germinal center (GC) response decline with age, resulting
in poor vaccine-induced immunity in older individuals. A functional GC requires the co …
in poor vaccine-induced immunity in older individuals. A functional GC requires the co …
Adverse outcomes of SARS-CoV-2 infection with delta and omicron variants in vaccinated versus unvaccinated US veterans: retrospective cohort study
ASB Bohnert, K Kumbier, M Rowneki, A Gupta… - bmj, 2023 - bmj.com
Objectives To determine the association between covid-19 vaccination types and doses with
adverse outcomes of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) …
adverse outcomes of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) …
COVID-19 outbreak in an elderly care home: very low vaccine effectiveness and late impact of booster vaccination campaign
CE van Ewijk, EI Hazelhorst, SJM Hahné, MJ Knol - Vaccine, 2022 - Elsevier
Background Elderly people in long-term care facilities (LTCF) are at higher risk for (severe)
COVID-19, yet evidence of vaccine effectiveness (VE) in this population is scarce. In …
COVID-19, yet evidence of vaccine effectiveness (VE) in this population is scarce. In …
[HTML][HTML] Safety and effectiveness of the booster dose of mRNA COVID-19 vaccines in people with multiple sclerosis: A monocentric experience
A Bertozzi, A Mariottini, L Marchi, M Di Cristinzi… - Multiple Sclerosis and …, 2023 - Elsevier
Background Long-term data on the effectiveness and safety of the booster dose of anti-
SARS-CoV-2 vaccines in people affected by multiple sclerosis (pwMS) are lacking, hence a …
SARS-CoV-2 vaccines in people affected by multiple sclerosis (pwMS) are lacking, hence a …
[HTML][HTML] Third dose of COVID-19 mRNA vaccine closes the gap in immune response between naïve nursing home residents and healthy adults
P Pannus, S Depickère, D Kemlin, D Georges… - Vaccine, 2023 - Elsevier
Background Nursing home residents, a frail and old population group, respond poorly to
primary mRNA COVID-19 vaccination. A third dose has been shown to boost protection …
primary mRNA COVID-19 vaccination. A third dose has been shown to boost protection …
Clinical effectiveness of SARS-CoV-2 booster vaccine against Omicron infection in residents and staff of Long-Term Care Facilities: a prospective cohort study …
Background Successive severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
variants have caused severe disease in long-term care facility (LTCF) residents. Primary …
variants have caused severe disease in long-term care facility (LTCF) residents. Primary …
[HTML][HTML] Will Omics Biotechnologies Save Us from Future Pandemics? Lessons from COVID-19 for Vaccinomics and Adversomics
A Ferraresi, C Isidoro - Biomedicines, 2022 - mdpi.com
The COVID-19 pandemic had cross-cutting impacts on planetary health, quotidian life, and
society. Mass vaccination with the current gene-based vaccines has helped control the …
society. Mass vaccination with the current gene-based vaccines has helped control the …
Effectiveness of successive booster vaccine doses against SARS-CoV-2 related mortality in residents of long-term care facilities in the VIVALDI study
Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused
severe disease in unvaccinated long-term care facility (LTCF) residents. Initial booster …
severe disease in unvaccinated long-term care facility (LTCF) residents. Initial booster …
COVID-19 vaccine hesitancy in care home staff: a survey of Liverpool care homes
JSP Tulloch, K Lawrenson, AL Gordon, S Ghebrehewet… - Vaccine, 2023 - Elsevier
Uptake of COVID-19 vaccine first doses in UK care homes has been higher among residents
compared to staff. We aimed to identify causes of lower COVID-19 vaccine uptake amongst …
compared to staff. We aimed to identify causes of lower COVID-19 vaccine uptake amongst …
[HTML][HTML] Protection from infection and reinfection due to the Omicron BA. 1 variant in care homes
S Choudhry, TAJ Rowland, K McClelland… - Frontiers in …, 2023 - frontiersin.org
Introduction Following the emergence of SARS-CoV-2 in 2020, care homes were
disproportionately impacted by high mortality and morbidity of vulnerable elderly residents …
disproportionately impacted by high mortality and morbidity of vulnerable elderly residents …