Role of metallothionein in cadmium traffic and toxicity in kidneys and other mammalian organs

I Sabolić, D Breljak, M Škarica, CM Herak-Kramberger - Biometals, 2010 - Springer
Metallothioneins are cysteine-rich, small metal-binding proteins present in various
mammalian tissues. Of the four common metallothioneins, MT-1 and MT-2 (MTs) are …

Deranged hepatocyte intracellular Ca2+ homeostasis and the progression of non-alcoholic fatty liver disease to hepatocellular carcinoma

ES Ali, GY Rychkov, GJ Barritt - Cell calcium, 2019 - Elsevier
Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related deaths in
men, and the sixth in women. Non-alcoholic fatty liver disease (NAFLD) is now one of the …

Pharmacological correction of obesity-induced autophagy arrest using calcium channel blockers

HW Park, H Park, IA Semple, I Jang, SH Ro… - Nature …, 2014 - nature.com
Autophagy deregulation during obesity contributes to the pathogenesis of diverse metabolic
disorders. However, without understanding the molecular mechanism of obesity interference …

Protective effect of Vitamin D3 against lead induced hepatotoxicity, oxidative stress, immunosuppressive and calcium homeostasis disorders in rat

H Almasmoum, B Refaat, MM Ghaith… - Environmental …, 2019 - Elsevier
Lead (Pb) is an extremely poisonous, non-essential trace element and toxicity develops in
humans following frequent exposure to the heavy metal in polluted environmental and …

Evaluation of the level of selected iron-related proteins/receptors in the liver of rats during separate/combined vanadium and magnesium administration

A Ścibior, I Hus, J Mańko, D Jawniak - … of Trace Elements in Medicine and …, 2020 - Elsevier
Background The current knowledge about the effects of vanadium (V) on iron (Fe)-related
proteins and Fe homeostasis (which is regulated at the systemic, organelle, and cellular …

Cloning of the Cav 1.3 (α1D) L-type Ca2+ channel from mouse and its expression in the liver

T Okamoto, T Kobayashi… - … journal of molecular …, 2004 - spandidos-publications.com
Abstract Dihydropyridine (DHP) type Ca2+ channel blocker (CCB) is effective in treatment of
hepatitis in man. L-type Ca2+ channel is a target of DHP-CCB, and basic studies suggest …

[PDF][PDF] Implication of histone H1 0-derived 17-kDa DNase in tamoxifen-induced apoptosis in aflatoxin B 1-elicited rat hepatocellular carcinoma cells

Y Kawasaki, N Adachi, I Tamura, T Komeno… - JSM …, 2014 - scholar.archive.org
2Department of Health Chemistry, School of Pharmacy, Iwate Medical University,
Nishitokuta 2-1-1, Yahaba, Shiwa-gun, Iwate 028-3694, Japan 3Division of Biochemistry …

[PDF][PDF] Deranged hepatocyte intracellular Ca 2 homeostasis and the progression of non-alcoholic fatty liver disease to hepatocellular carcinoma

ES Alia, GY Rychkovb, GJ Barritta - Cell Calcium, 2019 - academia.edu
Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related deaths in
men, and the sixth in women. Non-alcoholic fatty liver disease (NAFLD) is now one of the …

[PDF][PDF] COVALENT DRUG BINDING: A MECHANISTIC EXPLORATION TO ENHANCE SAFETY AND EFFICACY

CC YIP - 2015 - core.ac.uk
COVALENT DRUG BINDING: A MECHANISTIC EXPLORATION TO ENHANCE SAFETY AND
EFFICACY CHAN CHUN YIP (B.Sc. Pharm (Hons.), NUS) A THES Page 1 COVALENT DRUG …

[图书][B] Role of Hfe and hepcidin in the homeostasis of body iron levels

MSD Mascarenhas - 2007 - search.proquest.com
Recent studies have suggested that hepatic iron stores and the response to anaemia and
inflammation are dependent on the mouse strains used and their Hfe status. Hepcidin and …