All causes of renal allograft injury, when severe and/or sustained, can result in chronic
histological damage of which interstitial fibrosis and tubular atrophy are dominant features …

Crosstalk between B and T cells in transplantation is increasingly recognized as being
important in the alloimmune response. T cell activation of B cells occurs by a 3-stage …

The aim of this study was to investigate the role of infiltrating macrophages in renal allograft
fibrosis. Forty-six protocol renal allograft biopsies obtained 1 year after transplantation were …

Emerging molecular analysis can be used as an objective and independent assessment of
histopathological scoring systems. We compared the existing Banff i-score to the total …

We hypothesized that the gut microbiota influences survival of murine cardiac allografts
through modulation of immunity. Antibiotic pretreated mice received vascularized cardiac …

Inflammation impairs renal allograft survival but is difficult to quantify by eye at low densities.
Here we measured leukocyte abundance in early surveillance biopsies by digital image …

In the Banff consensus, infiltrates in areas of scarring are ignored. This study aimed to
characterize the molecular correlates and clinical significance of scarring and inflammation …

To assess the significance of B-cell and plasma cell infiltrates in renal allografts, we
compared expression of B-cell-associated transcripts (BATs) and immunoglobulin …

B cells and their immunoglobulin products participate in allograft rejection of transplanted
human kidneys in which an interesting feature is the presence of a germinal center like B …

Banff defines T-cell-mediated rejection (TCMR) using nonspecific lesions and arbitrary
cutoffs, with no external gold standard. We reexamined features of TCMR using exclusively …